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    SMAD1 SMAD family member 1 [ Tursiops truncatus (common bottlenose dolphin) ]

    Gene ID: 101320969, updated on 8-Mar-2024

    Summary

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    Gene symbol
    SMAD1
    Gene description
    SMAD family member 1
    See related
    EnsemblRapid:ENSTTRG00000008086
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Tursiops truncatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Tursiops
    Orthologs
    human mouse all
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    Genomic context

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    See SMAD1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current mTurTru1.mat.Y (GCF_011762595.1) 5 NC_047038.1 (113092399..113169963, complement)
    101 previous assembly NIST Tur_tru v1 (GCF_001922835.1) Unplaced Scaffold NW_017842585.1 (22822632..22900225)

    Chromosome 5 - NC_047038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117312441 Neighboring gene metabolism of cobalamin associated A Neighboring gene 40S ribosomal protein S23-like Neighboring gene OTU deubiquitinase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Tursiops truncatus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mTurTru1.mat.Y Primary Assembly

    Genomic

    1. NC_047038.1 Reference mTurTru1.mat.Y Primary Assembly

      Range
      113092399..113169963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004310545.3 → XP_004310593.1  mothers against decapentaplegic homolog 1 isoform X1

      See identical proteins and their annotated locations for XP_004310593.1

      UniProtKB/TrEMBL
      A0A2U4AM99
      Conserved Domains (3) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
      PRK10263
      Location:133 → 246
      PRK10263; DNA translocase FtsK; Provisional

    2. XM_019926537.2 → XP_019782096.1  mothers against decapentaplegic homolog 1 isoform X2

      UniProtKB/TrEMBL
      A0A2U4AMD5
      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:226 → 426
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    3. XM_033857325.1 → XP_033713216.1  mothers against decapentaplegic homolog 1 isoform X3

      UniProtKB/TrEMBL
      A0A6J3REL8
      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:140 → 340
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    4. XM_033857324.1 → XP_033713215.1  mothers against decapentaplegic homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A2U4AM99
      Conserved Domains (3) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
      PRK10263
      Location:133 → 246
      PRK10263; DNA translocase FtsK; Provisional

    5. XM_019926533.1 → XP_019782092.1  mothers against decapentaplegic homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A2U4AM99
      Conserved Domains (3) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
      PRK10263
      Location:133 → 246
      PRK10263; DNA translocase FtsK; Provisional

    6. XM_019926535.2 → XP_019782094.1  mothers against decapentaplegic homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A2U4AM99
      Conserved Domains (3) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
      PRK10263
      Location:133 → 246
      PRK10263; DNA translocase FtsK; Provisional

    7. XM_019926534.1 → XP_019782093.1  mothers against decapentaplegic homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A2U4AM99
      Related
      ENSTTRP00000007646.1, ENSTTRT00000008079.2
      Conserved Domains (3) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
      PRK10263
      Location:133 → 246
      PRK10263; DNA translocase FtsK; Provisional
    Nucleotide Protein
    Heading Accession and Version

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