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    REL REL proto-oncogene, NF-kB subunit [ Sus scrofa (pig) ]

    Gene ID: 100525104, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RELprovided by VGNC
    Official Full Name
    REL proto-oncogene, NF-kB subunitprovided by VGNC
    Primary source
    VGNC:VGNC:92202
    See related
    Ensembl:ENSSSCG00000008388
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Broad expression in spleen (RPKM 4.9), lung (RPKM 3.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (80861862..80912233, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (84966717..85003490, complement)

    Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene cytochrome c pseudogene Neighboring gene SANT and BTB domain regulator of CSR Neighboring gene peroxisomal biogenesis factor 13 Neighboring gene pseudouridine synthase 10 Neighboring gene poly(A) polymerase gamma Neighboring gene uncharacterized LOC102167754

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to cytokine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proto-oncogene c-Rel
    Names
    v-rel reticuloendotheliosis viral oncogene homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

      Range
      80861862..80912233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005662527.3 → XP_005662584.1  proto-oncogene c-Rel isoform X1

      UniProtKB/TrEMBL
      A0A287BI09, A0A4X1WBL8, A0A4X1WBX7, A0A8D0LXS9
      Related
      ENSSSCP00000055999.3, ENSSSCT00000054060.3
      Conserved Domains (2) summary
      pfam16179
      Location:187 → 282
      RHD_dimer; Rel homology dimerization domain
      cl08275
      Location:8 → 179
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

    2. XM_013996137.2 → XP_013851591.1  proto-oncogene c-Rel isoform X2

      UniProtKB/TrEMBL
      A0A4X1WBX7, A0A8D1SJR7
      Conserved Domains (2) summary
      pfam16179
      Location:187 → 282
      RHD_dimer; Rel homology dimerization domain
      cl08275
      Location:8 → 179
      RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)
    Nucleotide Protein
    Heading Accession and Version

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