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    NFATC4 nuclear factor of activated T cells 4 [ Sarcophilus harrisii (Tasmanian devil) ]

    Gene ID: 100920502, updated on 8-Mar-2024

    Summary

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    Gene symbol
    NFATC4
    Gene description
    nuclear factor of activated T cells 4
    See related
    Ensembl:ENSSHAG00000006860
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sarcophilus harrisii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus
    Orthologs
    human mouse all
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    Genomic context

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    See NFATC4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current mSarHar1.11 (GCF_902635505.1) 2 NC_045427.1 (495332975..495345263)
    102 previous assembly Devil_ref v7.0 (GCF_000189315.1) 1 Unlocalized Scaffold NW_003816508.1 (265116..276165)

    Chromosome 2 - NC_045427.1Genomic Context describing neighboring genes Neighboring gene leukotriene B4 receptor Neighboring gene adenylate cyclase 4 Neighboring gene NYN domain and retroviral integrase containing Neighboring gene cerebellin 3 precursor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcineurin-NFAT signaling cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear factor of activated T-cells, cytoplasmic 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sarcophilus harrisii Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mSarHar1.11 Primary Assembly

    Genomic

    1. NC_045427.1 Reference mSarHar1.11 Primary Assembly

      Range
      495332975..495345263
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031955104.1 → XP_031810964.1  nuclear factor of activated T-cells, cytoplasmic 4

      UniProtKB/TrEMBL
      A0A7N4PZM0, G3VXJ9
      Related
      ENSSHAP00000007904.2, ENSSHAT00000007967.2
      Conserved Domains (3) summary
      cd07881
      Location:410 → 583
      RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
      PHA03247
      Location:217 → 416
      PHA03247; large tegument protein UL36; Provisional
      cd01178
      Location:588 → 688
      IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
    Nucleotide Protein
    Heading Accession and Version

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