U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    PGR progesterone receptor [ Pan troglodytes (chimpanzee) ]

    Gene ID: 451502, updated on 10-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PGRprovided by VGNC
    Official Full Name
    progesterone receptorprovided by VGNC
    Primary source
    VGNC:VGNC:11682
    Locus tag
    CK820_G0031037
    See related
    Ensembl:ENSPTRG00000004206
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    PR; NR3C3
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PGR in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (103103292..103193527, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 11 NC_072409.1 (102331440..102422337, complement)

    Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 42 Neighboring gene COP9 signalosome complex subunit 5 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC104001300 Neighboring gene transient receptor potential cation channel subfamily C member 6 Neighboring gene putative monooxygenase p33MONOX

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The human progesterone receptor shows evidence of adaptive evolution associated with its ability to act as a transcription factor. Chen C, et al. Mol Phylogenet Evol, 2008 May. PMID 18375150, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables estrogen response element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear steroid receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear receptor-mediated steroid hormone signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    progesterone receptor
    Names
    Nuclear receptor subfamily 3 group C member 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135613.1 → NP_001129085.1  progesterone receptor

      See identical proteins and their annotated locations for NP_001129085.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ234980
      UniProtKB/Swiss-Prot
      A7X8B3
      UniProtKB/TrEMBL
      H2Q4L9
      Related
      ENSPTRP00000007237.6, ENSPTRT00000007845.6
      Conserved Domains (3) summary
      cd07074
      Location:686 → 933
      NR_LBD_PR; Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor
      cd07172
      Location:563 → 640
      NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
      pfam02161
      Location:1 → 564
      Prog_receptor; Progesterone receptor

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      103103292..103193527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063782550.1 → XP_063638620.1  progesterone receptor isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7X8B3.1 GenPept UniProtKB/Swiss-Prot:A7X8B3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials