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    smad1 SMAD family member 1 [ Oryzias latipes (Japanese medaka) ]

    Gene ID: 101155989, updated on 8-Mar-2024

    Summary

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    Gene symbol
    smad1
    Gene description
    SMAD family member 1
    See related
    EnsemblRapid:ENSORLG00000007377
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias latipes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Orthologs
    human zebrafish all
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    Genomic context

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    See smad1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    103 current ASM223467v1 (GCF_002234675.1) 1 NC_019859.2 (18355200..18375171)
    102 previous assembly ASM31367v1 (GCF_000313675.1) 1 NC_019859.1 (18115556..18135586)

    Chromosome 1 - NC_019859.2Genomic Context describing neighboring genes Neighboring gene Fras1 related extracellular matrix 3 Neighboring gene uncharacterized LOC101166773 Neighboring gene hedgehog interacting protein Neighboring gene metabolism of cobalamin associated A Neighboring gene zinc finger protein 827

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM223467v1 Primary Assembly

    Genomic

    1. NC_019859.2 Reference ASM223467v1 Primary Assembly

      Range
      18355200..18375171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004065930.4 → XP_004065978.1  mothers against decapentaplegic homolog 1

      UniProtKB/TrEMBL
      A0A3P9I7Z5, A0A3P9L712, H2LT29
      Related
      ENSORLP00000009247.2, ENSORLT00000009248.3
      Conserved Domains (2) summary
      cd10490
      Location:9 → 132
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:271 → 471
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
    Nucleotide Protein
    Heading Accession and Version

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