U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    HNF1B HNF1 homeobox B [ Ornithorhynchus anatinus (platypus) ]

    Gene ID: 100078334, updated on 30-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    HNF1B
    Gene description
    HNF1 homeobox B
    See related
    Ensembl:ENSOANG00000007132
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ornithorhynchus anatinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See HNF1B in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    105 current mOrnAna1.pri.v4 (GCF_004115215.2) 17 NC_041744.1 (14867459..14937446, complement)

    Chromosome 17 - NC_041744.1Genomic Context describing neighboring genes Neighboring gene DExD-box helicase 52 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene uncharacterized LOC114817718

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_041744.1 Chromosome 17 Reference mOrnAna1.pri.v4 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in liver development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in pancreas development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    hepatocyte nuclear factor 1-beta

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mOrnAna1.pri.v4 Primary Assembly

    Genomic

    1. NC_041744.1 Reference mOrnAna1.pri.v4 Primary Assembly

      Range
      14867459..14937446 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029082591.2 → XP_028938424.1  hepatocyte nuclear factor 1-beta isoform X4

      UniProtKB/TrEMBL
      F6PUY7
      Conserved Domains (3) summary
      cd00086
      Location:206 → 279
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam04812
      Location:288 → 527
      HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
      pfam04814
      Location:8 → 173
      HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus

    2. XM_029082589.1 → XP_028938422.1  hepatocyte nuclear factor 1-beta isoform X3

      UniProtKB/TrEMBL
      A0A6I8NL55, F6PUY7
      Related
      ENSOANP00000041402.1, ENSOANT00000060619.1
      Conserved Domains (3) summary
      cd00086
      Location:232 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam04812
      Location:314 → 553
      HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
      pfam04814
      Location:8 → 173
      HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus

    3. XM_029082588.1 → XP_028938421.1  hepatocyte nuclear factor 1-beta isoform X2

      UniProtKB/TrEMBL
      A0A6I8ND45, F6PUY7
      Related
      ENSOANP00000039133.1, ENSOANT00000063442.1
      Conserved Domains (3) summary
      cd00086
      Location:206 → 279
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam04812
      Location:288 → 527
      HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
      pfam04814
      Location:8 → 173
      HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus

    4. XM_029082587.2 → XP_028938420.1  hepatocyte nuclear factor 1-beta isoform X1

      UniProtKB/TrEMBL
      F6PUY7
      Related
      ENSOANP00000011347.2
      Conserved Domains (3) summary
      cd00086
      Location:232 → 305
      homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
      pfam04812
      Location:314 → 553
      HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C-terminus
      pfam04814
      Location:8 → 173
      HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N-terminus
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.