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    HEY2 hes related family bHLH transcription factor with YRPW motif 2 [ Mustela putorius furo (domestic ferret) ]

    Gene ID: 101673422, updated on 8-Mar-2024

    Summary

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    Gene symbol
    HEY2
    Gene description
    hes related family bHLH transcription factor with YRPW motif 2
    See related
    Ensembl:ENSMPUG00000014531
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mustela putorius furo (sub-species: furo)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
    Orthologs
    human mouse all
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    Genomic context

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    See HEY2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025422015.1 (27543535..27554589, complement)
    101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569146.1 (19890356..19895116)

    NW_025422015.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor coactivator 7 Neighboring gene uncharacterized LOC123387855 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene U4 spliceosomal RNA Neighboring gene 60S acidic ribosomal protein P1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequencing, annotation, and characterization of the influenza ferret infectome. León AJ, et al. J Virol, 2013 Feb. PMID 23236062, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anterior/posterior pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in circulatory system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of neurogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hairy/enhancer-of-split related with YRPW motif protein 2
    Names
    hairy/enhancer-of-split related with YRPW motif 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1176430v1.1 Primary Assembly

    Genomic

    1. NW_025422015.1 Reference ASM1176430v1.1 Primary Assembly

      Range
      27543535..27554589 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045066401.1 → XP_044922336.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8U0RFJ6
      Conserved Domains (2) summary
      smart00511
      Location:119 → 165
      ORANGE; Orange domain
      cd18920
      Location:40 → 121
      bHLH-O_HEY2; basic helix-loop-helix-orange (bHLH-O) domain found in hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) and similar proteins

    2. XM_045066400.1 → XP_044922335.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8U0UNN6
      Conserved Domains (2) summary
      smart00511
      Location:119 → 165
      ORANGE; Orange domain
      cd18920
      Location:40 → 121
      bHLH-O_HEY2; basic helix-loop-helix-orange (bHLH-O) domain found in hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) and similar proteins

    3. XM_045066402.1 → XP_044922337.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8U0RFL5
      Conserved Domains (2) summary
      smart00511
      Location:73 → 119
      ORANGE; Orange domain
      cl00081
      Location:1 → 75
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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