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    TCF7 transcription factor 7 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710234, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TCF7provided by VGNC
    Official Full Name
    transcription factor 7provided by VGNC
    Primary source
    VGNC:VGNC:84506
    See related
    Ensembl:ENSMMUG00000022788
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See TCF7 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (131551558..131584973)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (131806953..131839698)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene chromosome 6 C5orf15 homolog Neighboring gene uncharacterized LOC106998947 Neighboring gene voltage dependent anion channel 1 Neighboring gene S-phase kinase associated protein 1 Neighboring gene protein phosphatase 2 catalytic subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of beta-catenin-TCF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor 7
    Names
    transcription factor 7 (T-cell specific, HMG-box)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      131551558..131584973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849722.1 → XP_028705555.1  transcription factor 7 isoform X1

      UniProtKB/TrEMBL
      F7C2J4
      Related
      ENSMMUP00000034129.3, ENSMMUT00000041095.3
      Conserved Domains (2) summary
      cd01388
      Location:304 → 374
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    2. XM_015140915.2 → XP_014996401.2  transcription factor 7 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QY59
      Conserved Domains (2) summary
      cd01388
      Location:304 → 374
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    3. XM_028849723.1 → XP_028705556.1  transcription factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QY59
      Related
      ENSMMUP00000030002.4, ENSMMUT00000032065.4
      Conserved Domains (2) summary
      cd01388
      Location:304 → 374
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    4. XM_015140919.2 → XP_014996405.2  transcription factor 7 isoform X7

      UniProtKB/TrEMBL
      A0A1D5QY59
      Conserved Domains (2) summary
      cd01388
      Location:273 → 343
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    5. XM_028849727.1 → XP_028705560.1  transcription factor 7 isoform X6

      UniProtKB/TrEMBL
      A0A1D5QY59
      Related
      ENSMMUP00000052990.2, ENSMMUT00000072920.2
      Conserved Domains (2) summary
      cd01388
      Location:273 → 343
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    6. XM_015140914.2 → XP_014996400.2  transcription factor 7 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QY59
      Conserved Domains (2) summary
      cd01388
      Location:304 → 374
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:20 → 216
      CTNNB1_binding; N-terminal CTNNB1 binding

    7. XM_028849728.1 → XP_028705561.1  transcription factor 7 isoform X8

      Conserved Domains (2) summary
      cd01388
      Location:185 → 255
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:1 → 97
      CTNNB1_binding; N-terminal CTNNB1 binding

    8. XM_015140918.2 → XP_014996404.1  transcription factor 7 isoform X10

      UniProtKB/TrEMBL
      F6V4P6
      Conserved Domains (2) summary
      cd01388
      Location:154 → 224
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      pfam08347
      Location:1 → 97
      CTNNB1_binding; N-terminal CTNNB1 binding

    9. XM_015140917.2 → XP_014996403.1  transcription factor 7 isoform X9

      Conserved Domains (2) summary
      cd01388
      Location:154 → 224
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      pfam08347
      Location:1 → 97
      CTNNB1_binding; N-terminal CTNNB1 binding

    10. XM_028849725.1 → XP_028705558.1  transcription factor 7 isoform X5

      UniProtKB/TrEMBL
      G7MUC1
      Conserved Domains (2) summary
      cd01388
      Location:185 → 255
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:1 → 97
      CTNNB1_binding; N-terminal CTNNB1 binding

    11. XM_028849724.1 → XP_028705557.1  transcription factor 7 isoform X5

      UniProtKB/TrEMBL
      G7MUC1
      Conserved Domains (2) summary
      cd01388
      Location:185 → 255
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:1 → 97
      CTNNB1_binding; N-terminal CTNNB1 binding
    Nucleotide Protein
    Heading Accession and Version

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