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    LEF1 lymphoid enhancer binding factor 1 [ Myotis lucifugus (little brown bat) ]

    Gene ID: 102439262, updated on 30-Mar-2024

    Summary

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    Gene symbol
    LEF1
    Gene description
    lymphoid enhancer binding factor 1
    See related
    Ensembl:ENSMLUG00000008891
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Myotis lucifugus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
    Orthologs
    human mouse all
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    Genomic context

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    See LEF1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    102 current Myoluc2.0 (GCF_000147115.1) Unplaced Scaffold NW_005871230.1 (348110..457877)

    NW_005871230.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-like protein FUBI pseudogene Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene hydroxyacyl-CoA dehydrogenase Neighboring gene cytochrome P450 2U1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_005871230 Unplaced Scaffold Reference Myoluc2.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of beta-catenin-TCF complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lymphoid enhancer-binding factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Myotis lucifugus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Myoluc2.0

    Genomic

    1. NW_005871230.1 Reference Myoluc2.0

      Range
      348110..457877
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014462481.2 → XP_014317967.1  lymphoid enhancer-binding factor 1 isoform X2

      UniProtKB/TrEMBL
      G1PCG0
      Related
      ENSMLUP00000008101.2, ENSMLUT00000008889.2
      Conserved Domains (2) summary
      cd01388
      Location:183 → 254
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      pfam08347
      Location:1 → 98
      CTNNB1_binding; N-terminal CTNNB1 binding

    2. XM_023760458.1 → XP_023616226.1  lymphoid enhancer-binding factor 1 isoform X1

      UniProtKB/TrEMBL
      G1PCG0
      Conserved Domains (2) summary
      cd01388
      Location:183 → 254
      SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
      pfam08347
      Location:1 → 98
      CTNNB1_binding; N-terminal CTNNB1 binding

    3. XM_006096583.3 → XP_006096645.1  lymphoid enhancer-binding factor 1 isoform X3

      UniProtKB/TrEMBL
      G1PCG0
      Conserved Domains (2) summary
      cd01388
      Location:155 → 226
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      pfam08347
      Location:1 → 98
      CTNNB1_binding; N-terminal CTNNB1 binding
    Nucleotide Protein
    Heading Accession and Version

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