U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SMAD3 SMAD family member 3 [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105857966, updated on 13-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    SMAD3
    Gene description
    SMAD family member 3
    See related
    Ensembl:ENSMICG00000006119
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SMAD3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 3 NC_033662.1 (98305786..98420125, complement)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195491.1 (276090..387249, complement)

    Chromosome 3 - NC_033662.1Genomic Context describing neighboring genes Neighboring gene IQ domain-containing protein H-like Neighboring gene alpha and gamma adaptin binding protein Neighboring gene uncharacterized LOC105857988 Neighboring gene uncharacterized LOC105857992 Neighboring gene LETM1 and EF-hand domain-containing protein 1, mitochondrial pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    mothers against decapentaplegic homolog 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033662.1 Reference Mmur_3.0 Primary Assembly

      Range
      98305786..98420125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012740758.2 → XP_012596212.1  mothers against decapentaplegic homolog 3 isoform X1

      See identical proteins and their annotated locations for XP_012596212.1

      UniProtKB/TrEMBL
      A0A8C5VP50, A0A8C5YBL9
      Related
      ENSMICP00000048645.1, ENSMICT00000059316.1
      Conserved Domains (2) summary
      cd10491
      Location:8 → 132
      MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
      cd10985
      Location:224 → 414
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

    2. XM_012740765.2 → XP_012596219.1  mothers against decapentaplegic homolog 3 isoform X2

      UniProtKB/TrEMBL
      A0A8B7EQ44, A0A8C5URB4
      Related
      ENSMICP00000041603.1, ENSMICT00000059541.1
      Conserved Domains (2) summary
      cd10985
      Location:171 → 361
      MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3
      cl00055
      Location:12 → 79
      MH1; N-terminal Mad Homology 1 (MH1) domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.