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    L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105855537, updated on 13-Mar-2024

    Summary

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    Gene symbol
    L3MBTL3
    Gene description
    L3MBTL histone methyl-lysine binding protein 3
    See related
    Ensembl:ENSMICG00000006114
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
    human mouse all
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    Genomic context

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    See L3MBTL3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 6 NC_033665.1 (88801366..88908757)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012199075.1 (2381550..2488802)

    Chromosome 6 - NC_033665.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 18 Neighboring gene transmembrane protein 244 Neighboring gene uncharacterized LOC105855539 Neighboring gene sterile alpha motif domain containing 3 Neighboring gene transmembrane protein 200A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal(3)malignant brain tumor-like protein 3
    Names
    L3MBTL3, histone methyl-lysine binding protein
    l(3)mbt-like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033665.1 Reference Mmur_3.0 Primary Assembly

      Range
      88801366..88908757
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012736593.2 → XP_012592047.1  lethal(3)malignant brain tumor-like protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A8B7ECX1
      Conserved Domains (4) summary
      cd09582
      Location:704 → 769
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:704 → 770
      SAM; Sterile alpha motif
      smart00561
      Location:236 → 332
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:557 → 584
      zf-C2HC; Zinc finger, C2HC type

    2. XM_012736595.2 → XP_012592049.1  lethal(3)malignant brain tumor-like protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8C6EH44
      Related
      ENSMICP00000041976.1, ENSMICT00000063724.1
      Conserved Domains (3) summary
      cd09582
      Location:679 → 744
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:211 → 307
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:532 → 561
      zf-C2HC; Zinc finger, C2HC type

    3. XM_012736585.2 → XP_012592039.1  lethal(3)malignant brain tumor-like protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8B7ED28
      Conserved Domains (4) summary
      cd09582
      Location:736 → 801
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:736 → 802
      SAM; Sterile alpha motif
      smart00561
      Location:268 → 364
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:589 → 616
      zf-C2HC; Zinc finger, C2HC type

    4. XM_012736584.2 → XP_012592038.1  lethal(3)malignant brain tumor-like protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8B7ECG1
      Conserved Domains (4) summary
      cd09582
      Location:737 → 802
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:737 → 803
      SAM; Sterile alpha motif
      smart00561
      Location:269 → 365
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:590 → 617
      zf-C2HC; Zinc finger, C2HC type

    5. XM_012736586.2 → XP_012592040.1  lethal(3)malignant brain tumor-like protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8B7ECG9
      Conserved Domains (4) summary
      cd09582
      Location:732 → 797
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:732 → 798
      SAM; Sterile alpha motif
      smart00561
      Location:264 → 360
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:585 → 612
      zf-C2HC; Zinc finger, C2HC type

    6. XM_012736587.2 → XP_012592041.1  lethal(3)malignant brain tumor-like protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8C5VMR4
      Related
      ENSMICP00000026374.2, ENSMICT00000039181.2
      Conserved Domains (4) summary
      cd09582
      Location:712 → 777
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:712 → 778
      SAM; Sterile alpha motif
      smart00561
      Location:244 → 340
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:565 → 592
      zf-C2HC; Zinc finger, C2HC type

    7. XM_012736588.2 → XP_012592042.1  lethal(3)malignant brain tumor-like protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A8B7ECW5
      Conserved Domains (4) summary
      cd09582
      Location:711 → 776
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:711 → 777
      SAM; Sterile alpha motif
      smart00561
      Location:243 → 339
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:564 → 591
      zf-C2HC; Zinc finger, C2HC type

    8. XM_012736589.1 → XP_012592043.1  lethal(3)malignant brain tumor-like protein 3 isoform X6

      See identical proteins and their annotated locations for XP_012592043.1

      UniProtKB/TrEMBL
      A0A8B7EF41
      Related
      ENSMICP00000005572.2, ENSMICT00000006113.3
      Conserved Domains (4) summary
      cd09582
      Location:705 → 770
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:705 → 771
      SAM; Sterile alpha motif
      smart00561
      Location:237 → 333
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:558 → 585
      zf-C2HC; Zinc finger, C2HC type

    9. XM_012736594.1 → XP_012592048.1  lethal(3)malignant brain tumor-like protein 3 isoform X8

      UniProtKB/TrEMBL
      A0A8B7ECH0
      Related
      ENSMICP00000036023.2, ENSMICT00000040331.2
      Conserved Domains (4) summary
      cd09582
      Location:680 → 745
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:680 → 746
      SAM; Sterile alpha motif
      smart00561
      Location:212 → 308
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:533 → 560
      zf-C2HC; Zinc finger, C2HC type

    10. XM_020287199.1 → XP_020142788.1  lethal(3)malignant brain tumor-like protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8C6EH44
      Conserved Domains (3) summary
      cd09582
      Location:679 → 744
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00561
      Location:211 → 307
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:532 → 561
      zf-C2HC; Zinc finger, C2HC type

    11. XM_012736591.2 → XP_012592045.1  lethal(3)malignant brain tumor-like protein 3 isoform X6

      See identical proteins and their annotated locations for XP_012592045.1

      UniProtKB/TrEMBL
      A0A8B7EF41
      Conserved Domains (4) summary
      cd09582
      Location:705 → 770
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:705 → 771
      SAM; Sterile alpha motif
      smart00561
      Location:237 → 333
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:558 → 585
      zf-C2HC; Zinc finger, C2HC type

    12. XM_012736590.2 → XP_012592044.1  lethal(3)malignant brain tumor-like protein 3 isoform X6

      See identical proteins and their annotated locations for XP_012592044.1

      UniProtKB/TrEMBL
      A0A8B7EF41
      Conserved Domains (4) summary
      cd09582
      Location:705 → 770
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:705 → 771
      SAM; Sterile alpha motif
      smart00561
      Location:237 → 333
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:558 → 585
      zf-C2HC; Zinc finger, C2HC type

    13. XM_012736592.2 → XP_012592046.1  lethal(3)malignant brain tumor-like protein 3 isoform X6

      See identical proteins and their annotated locations for XP_012592046.1

      UniProtKB/TrEMBL
      A0A8B7EF41
      Conserved Domains (4) summary
      cd09582
      Location:705 → 770
      SAM_Scm-like-3MBT3,4; SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group
      smart00454
      Location:705 → 771
      SAM; Sterile alpha motif
      smart00561
      Location:237 → 333
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam01530
      Location:558 → 585
      zf-C2HC; Zinc finger, C2HC type
    Nucleotide Protein
    Heading Accession and Version

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