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    SMARCA5 SNF2 related chromatin remodeling ATPase 5 [ Microcebus murinus (gray mouse lemur) ]

    Gene ID: 105881859, updated on 20-Sep-2024

    Summary

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    Gene symbol
    SMARCA5
    Gene description
    SNF2 related chromatin remodeling ATPase 5
    See related
    Ensembl:ENSMICG00000003971
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Microcebus murinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
    Orthologs
    human mouse all
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    Genomic context

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    See SMARCA5 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    101 current Mmur_3.0 (GCF_000165445.2) 14 NC_033673.1 (58259111..58303467, complement)
    100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012197797.1 (11985930..12030014, complement)

    Chromosome 14 - NC_033673.1Genomic Context describing neighboring genes Neighboring gene glycophorin A (MNS blood group) Neighboring gene FRAS1 related extracellular matrix 3 Neighboring gene methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial-like Neighboring gene GRB2 associated binding protein 1 Neighboring gene translation initiation factor IF-2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
    Names
    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmur_3.0 Primary Assembly

    Genomic

    1. NC_033673.1 Reference Mmur_3.0 Primary Assembly

      Range
      58259111..58303467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012783805.1 → XP_012639259.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 isoform X1

      UniProtKB/TrEMBL
      A0A8B7HNF6, A0A8C5UNI4
      Related
      ENSMICP00000020203.1, ENSMICT00000054354.2
      Conserved Domains (7) summary
      smart00717
      Location:842 → 883
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00046
      Location:200 → 339
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00167
      Location:844 → 883
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00176
      Location:183 → 463
      SNF2_N; SNF2 family N-terminal domain
      pfam00271
      Location:482 → 597
      Helicase_C; Helicase conserved C-terminal domain
      pfam09110
      Location:743 → 828
      HAND; HAND
      pfam09111
      Location:898 → 1010
      SLIDE; SLIDE

    2. XM_012783806.1 → XP_012639260.1  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 isoform X2

      UniProtKB/TrEMBL
      A0A8B7HQ25, A0A8C5UNI4
      Related
      ENSMICP00000003625.3, ENSMICT00000003979.3
      Conserved Domains (1) summary
      cl26465
      Location:1 → 929
      SNF2_N; SNF2 family N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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