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    MEF2A myocyte enhancer factor 2A [ Loxodonta africana (African savanna elephant) ]

    Gene ID: 100655934, updated on 10-Oct-2024

    Summary

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    Gene symbol
    MEF2A
    Gene description
    myocyte enhancer factor 2A
    See related
    EnsemblRapid:ENSLAFG00000004656
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Loxodonta africana
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
    Orthologs
    human mouse all
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    Genomic context

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    See MEF2A in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 13 NC_087354.1 (14667718..14879977, complement)
    102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573448.1 (32410278..32621914)

    Chromosome 13 - NC_087354.1Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene LysM domain containing 4 Neighboring gene leucine rich repeat containing 28 Neighboring gene tetratricopeptide repeat domain 23

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myocyte-specific enhancer factor 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mLoxAfr1.hap2

    Genomic

    1. NC_087354.1 Reference mLoxAfr1.hap2

      Range
      14667718..14879977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023553063.2 → XP_023408831.1  myocyte-specific enhancer factor 2A isoform X1

      UniProtKB/TrEMBL
      G3SUN6
      Conserved Domains (3) summary
      cd00265
      Location:2 → 78
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam12347
      Location:97 → 152
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
      cl25496
      Location:143 → 372
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    2. XM_064267059.1 → XP_064123129.1  myocyte-specific enhancer factor 2A isoform X1

      Related
      ENSLAFP00000029655.1, ENSLAFT00000038401.1

    3. XM_064267060.1 → XP_064123130.1  myocyte-specific enhancer factor 2A isoform X2

      Related
      ENSLAFP00000023848.2, ENSLAFT00000026255.2

    4. XM_064267061.1 → XP_064123131.1  myocyte-specific enhancer factor 2A isoform X4

    5. XM_023553065.2 → XP_023408833.1  myocyte-specific enhancer factor 2A isoform X3

      UniProtKB/TrEMBL
      G3SUN6
      Conserved Domains (2) summary
      pfam12347
      Location:16 → 69
      HJURP_C; Holliday junction regulator protein family C-terminal repeat
      cl25496
      Location:60 → 230
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    Nucleotide Protein
    Heading Accession and Version

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