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    FLI1 Fli-1 proto-oncogene, ETS transcription factor [ Equus caballus (horse) ]

    Gene ID: 100064591, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FLI1provided by VGNC
    Official Full Name
    Fli-1 proto-oncogene, ETS transcription factorprovided by VGNC
    Primary source
    VGNC:VGNC:18058
    See related
    Ensembl:ENSECAG00000021051
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See FLI1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current EquCab3.0 (GCF_002863925.1) 7 NC_009150.3 (38498606..38610368)

    Chromosome 7 - NC_009150.3Genomic Context describing neighboring genes Neighboring gene ETS proto-oncogene 1, transcription factor Neighboring gene uncharacterized LOC111774258 Neighboring gene uncharacterized LOC102149585 Neighboring gene uncharacterized LOC106783356 Neighboring gene potassium inwardly rectifying channel subfamily J member 1 Neighboring gene potassium inwardly rectifying channel subfamily J member 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009150.3 Chromosome 7 Reference EquCab3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Friend leukemia integration 1 transcription factor
    Names
    Friend leukemia virus integration 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference EquCab3.0 Primary Assembly

    Genomic

    1. NC_009150.3 Reference EquCab3.0 Primary Assembly

      Range
      38498606..38610368
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001505100.6 → XP_001505150.1  Friend leukemia integration 1 transcription factor isoform X1

      See identical proteins and their annotated locations for XP_001505150.1

      UniProtKB/TrEMBL
      A0A9L0SR27, A0A9L0T1J0
      Related
      ENSECAP00000078511.1, ENSECAT00000139222.1
      Conserved Domains (2) summary
      cd08541
      Location:114 → 204
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:280 → 363
      ETS; erythroblast transformation specific domain

    2. XM_014741200.2 → XP_014596686.1  Friend leukemia integration 1 transcription factor isoform X2

      UniProtKB/TrEMBL
      A0A9L0T1J0
      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:247 → 330
      ETS; erythroblast transformation specific domain
    Nucleotide Protein
    Heading Accession and Version

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