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    mxd4 MAX dimerization protein 4 [ Danio rerio (zebrafish) ]

    Gene ID: 559531, updated on 2-Nov-2024

    Summary

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    Official Symbol
    mxd4provided by ZNC
    Official Full Name
    MAX dimerization protein 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-44
    See related
    Ensembl:ENSDARG00000054031 AllianceGenome:ZFIN:ZDB-GENE-050208-44
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mad4; im:7136512; si:ch211-145b13.8
    Summary
    Predicted to enable protein dimerization activity. Predicted to be located in nucleus. Is expressed in head mesenchyme; notochord; pronephric duct; and pronephric mesoderm. Orthologous to human MXD4 (MAX dimerization protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mxd4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (26071869..26097367)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (25378145..25403648)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene G patch domain and ankyrin repeats 1 Neighboring gene programmed cell death 4a Neighboring gene NADH:ubiquinone oxidoreductase subunit B Neighboring gene topoisomerase I binding, arginine/serine-rich a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. Shimada Y, et al. Int J Obes (Lond), 2014 Aug. PMID 24254064
    2. Phylogenetic analysis of zebrafish basic helix-loop-helix transcription factors. Wang Y, et al. J Mol Evol, 2009 Jun. PMID 19449054
    3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    max dimerization protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      26071869..26097367
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_682878.10 → XP_687970.6  max dimerization protein 4

      UniProtKB/TrEMBL
      A0A8N7TET9, E7F6Q1
      Related
      ENSDARP00000059263.5, ENSDART00000059264.6
      Conserved Domains (1) summary
      smart00353
      Location:58 → 110
      HLH; helix loop helix domain
    Nucleotide Protein Strain
    Heading Accession and Version

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