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    msxb msxb homeoprotein [ Ciona intestinalis (vase tunicate) ]

    Gene ID: 445677, updated on 21-Dec-2023

    Summary

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    Gene symbol
    msxb
    Gene description
    msxb homeoprotein
    See related
    Ensembl:ENSCING00000009129
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ciona intestinalis
    Lineage
    Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
    Also known as
    Ci-msxb
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    Genomic context

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    See msxb in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    104 current KH (GCF_000224145.3) 2 NC_020167.2 (5773526..5775829)

    Chromosome 2 - NC_020167.2Genomic Context describing neighboring genes Neighboring gene PRELI domain-containing protein 1, mitochondrial-like Neighboring gene glutamine--tRNA ligase-like Neighboring gene uncharacterized LOC108950884 Neighboring gene uncharacterized LOC100182818

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_020167.2 Chromosome 2 Reference KH Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Msxb is a core component of the genetic circuitry specifying the dorsal and ventral neurogenic midlines in the ascidian embryo. Roure A, et al. Dev Biol, 2016 Jan 1. PMID 26592100
    2. Regulatory elements controlling Ci-msxb tissue-specific expression during Ciona intestinalis embryonic development. Russo MT, et al. Dev Biol, 2004 Mar 15. PMID 15013810
    3. Identification and developmental expression of Ci-msxb: a novel homologue of Drosophila msh gene in Ciona intestinalis. Aniello F, et al. Mech Dev, 1999 Oct. PMID 10525197
    4. Transcriptional regulation of the retinoic acid receptor in the dorsal midline epidermis in the Ciona intestinalis embryo. Koyano R, et al. Dev Growth Differ, 2009 Dec. PMID 19824898
    5. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Imai KS, et al. Development, 2004 Aug. PMID 15269171

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Msxb would be the primary midline gene integrating inputs from the ventral and dorsal inducers and launching a pan-midline transcriptional program.
      Title: Msxb is a core component of the genetic circuitry specifying the dorsal and ventral neurogenic midlines in the ascidian embryo.
    2. Msxb and SoxB1 synergistically activate the RAR enhancer in the dorsal midline epidermis.
      Title: Transcriptional regulation of the retinoic acid receptor in the dorsal midline epidermis in the Ciona intestinalis embryo.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in embryonic morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    msxb homeoprotein
    Names
    transcription factor protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001032496.1 → NP_001027668.1  msxb homeoprotein

      See identical proteins and their annotated locations for NP_001027668.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ132758
      UniProtKB/TrEMBL
      A0A1W2VNB1, F6S3B3, Q9XZR1
      Related
      ENSCINP00000018527, ENSCINT00000018527
      Conserved Domains (1) summary
      pfam00046
      Location:184 → 237
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KH Primary Assembly

    Genomic

    1. NC_020167.2 Reference KH Primary Assembly

      Range
      5773526..5775829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials