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    STAT3 signal transducer and activator of transcription 3 [ Ailuropoda melanoleuca (giant panda) ]

    Gene ID: 100469938, updated on 11-Apr-2024

    Summary

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    Gene symbol
    STAT3
    Gene description
    signal transducer and activator of transcription 3
    Locus tag
    PANDA_011157
    See related
    Ensembl:ENSAMEG00000006266
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ailuropoda melanoleuca
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
    Orthologs
    human mouse all
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    Genomic context

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    See STAT3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current ASM200744v2 (GCF_002007445.1) 13 NC_048230.1 (26083879..26150727, complement)
    102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003217842.1 (797618..824546, complement)

    Chromosome 13 - NC_048230.1Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 5B Neighboring gene signal transducer and activator of transcription 5A Neighboring gene caveolae associated protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene ATPase H+ transporting V0 subunit a1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leptin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM200744v2 Primary Assembly

    Genomic

    1. NC_048230.1 Reference ASM200744v2 Primary Assembly

      Range
      26083879..26150727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034641687.1 → XP_034497578.1  signal transducer and activator of transcription 3 isoform X4

      UniProtKB/TrEMBL
      D2HIT4
      Conserved Domains (4) summary
      cd10374
      Location:554 → 714
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    2. XM_034641686.1 → XP_034497577.1  signal transducer and activator of transcription 3 isoform X3

      UniProtKB/TrEMBL
      D2HIT4
      Conserved Domains (4) summary
      cd10374
      Location:554 → 715
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    3. XM_034641685.1 → XP_034497576.1  signal transducer and activator of transcription 3 isoform X2

      UniProtKB/TrEMBL
      D2HIT4
      Conserved Domains (4) summary
      cd10374
      Location:554 → 714
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    4. XM_034641683.1 → XP_034497574.1  signal transducer and activator of transcription 3 isoform X1

      UniProtKB/TrEMBL
      D2HIT4
      Related
      ENSAMEP00000006689.2, ENSAMET00000006972.2
      Conserved Domains (4) summary
      cd10374
      Location:554 → 715
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    5. XM_034641688.1 → XP_034497579.1  signal transducer and activator of transcription 3 isoform X1

      UniProtKB/TrEMBL
      D2HIT4
      Conserved Domains (4) summary
      cd10374
      Location:554 → 715
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    Nucleotide Protein
    Heading Accession and Version

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