U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nav2 neuron navigator 2 [ Mus musculus (house mouse) ]

Gene ID: 78286, updated on 6-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Nav2provided by MGI
Official Full Name
neuron navigator 2provided by MGI
Primary source
MGI:MGI:2183691
See related
Ensembl:ENSMUSG00000052512 AllianceGenome:MGI:2183691
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HELAD1; RAINB1; RAINB2; POMFIL2; Unc53H2; mKIAA3015; 5330421F07Rik
Summary
Enables heparin binding activity. Involved in cerebellar cortex development. Acts upstream of or within several processes, including cranial nerve development; sensory perception of smell; and sensory perception of sound. Located in interstitial matrix. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb ectoderm; and somite. Orthologous to human NAV2 (neuron navigator 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 5.2), lung adult (RPKM 4.6) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Nav2 in Genome Data Viewer
Location:
7 B4; 7 31.23 cM
Exon count:
55
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (48608796..49259838)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (48959063..49610090)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3719 Neighboring gene STARR-positive B cell enhancer ABC_E8174 Neighboring gene STARR-seq mESC enhancer starr_18888 Neighboring gene STARR-seq mESC enhancer starr_18889 Neighboring gene predicted gene 2788 Neighboring gene STARR-seq mESC enhancer starr_18890 Neighboring gene E2F transcription factor 8 Neighboring gene RAN, member RAS oncogene family pseudogene Neighboring gene predicted gene, 32849 Neighboring gene RIKEN cDNA 9130015G15 gene Neighboring gene STARR-seq mESC enhancer starr_18892 Neighboring gene STARR-seq mESC enhancer starr_18893 Neighboring gene STARR-seq mESC enhancer starr_18894 Neighboring gene STARR-seq mESC enhancer starr_18895 Neighboring gene STARR-positive B cell enhancer mm9_chr7:56552487-56552788 Neighboring gene STARR-seq mESC enhancer starr_18896 Neighboring gene STARR-seq mESC enhancer starr_18898 Neighboring gene predicted gene, 51448 Neighboring gene STARR-seq mESC enhancer starr_18899 Neighboring gene predicted gene, 51447 Neighboring gene STARR-seq mESC enhancer starr_18905 Neighboring gene STARR-seq mESC enhancer starr_18907 Neighboring gene STARR-seq mESC enhancer starr_18909 Neighboring gene predicted gene, 32694 Neighboring gene predicted gene, 45985 Neighboring gene developing brain homeobox 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Expression pattern of Nav2 in the murine CNS with development. Pook C, et al. Gene Expr Patterns, 2020 Jan. PMID 32081718
  2. Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development. McNeill EM, et al. Dev Biol, 2011 May 15. PMID 21419114, Free PMC Article
  3. Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. Peeters PJ, et al. Brain Res Dev Brain Res, 2004 Jun 21. PMID 15158073
  4. Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Coy JF, et al. Gene, 2002 May 15. PMID 12062803
  5. Nav2 is necessary for cranial nerve development and blood pressure regulation. McNeill EM, et al. Neural Dev, 2010 Feb 25. PMID 20184720, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of novel genes including NAV2 associated with isolated tall stature.
    Title: Identification of novel genes including NAV2 associated with isolated tall stature.
  2. Expression pattern of Nav2 in the murine CNS with development.
    Title: Expression pattern of Nav2 in the murine CNS with development.
  3. essential role for full-length Nav2 in cerebellar development, including axonal elongation and migration of the external granule layer neurond
    Title: Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development.
  4. Data show that Nav2 functions in mammalian nervous system development, and is required for normal cranial nerve development and blood pressure regulation in the adult.
    Title: Nav2 is necessary for cranial nerve development and blood pressure regulation.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Gene trapped (1)  1 citation

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity ISO
Inferred from Sequence Orthology
more info
  
enables heparin binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within glossopharyngeal nerve development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within locomotory behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within optic nerve development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of systemic arterial blood pressure by baroreceptor feedback IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sensory perception of sound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within vagus nerve development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IDA
Inferred from Direct Assay
more info
 PubMed 
located_in interstitial matrix IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
neuron navigator 2
Names
retinoic acid inducible in neuroblastoma
NP_001104486.1
NP_780481.2
XP_006541351.1
XP_006541352.1
XP_006541356.1
XP_006541358.1
XP_006541360.1
XP_006541361.1
XP_006541362.1
XP_006541363.1
XP_006541365.1
XP_006541366.1
XP_006541369.1
XP_006541370.1
XP_006541371.1
XP_006541372.1
XP_006541373.1
XP_006541374.1
XP_017167885.1
XP_017167886.1
XP_030098971.1
XP_030098972.1
XP_030098973.1
XP_030098974.1
XP_030098975.1
XP_036009461.1
XP_036009462.1
XP_036009463.1
XP_036009464.1
XP_036009465.1
XP_036009466.1
XP_036009467.1
XP_036009468.1
XP_036009469.1
XP_036009470.1
XP_036009471.1
XP_036009472.1
XP_036009473.1
XP_036009474.1
XP_036009475.1
XP_036009476.1
XP_036009477.1
XP_036009478.1
XP_036009479.1
XP_036009480.1
XP_036009481.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111016.1 → NP_001104486.1  neuron navigator 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC119848, AK019901, AK040152, AK084063, AK129480, BM936768, BQ964922, CF580688, CF584312, CF584313, CF742564, CF743819, CF744797, CK781037, DV652788
    Consensus CDS
    CCDS71972.1
    UniProtKB/TrEMBL
    V9GXT3
    Related
    ENSMUSP00000139309.2, ENSMUST00000183659.8
    Conserved Domains (5) summary
    smart00382
    Location:2033 → 2141
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:22 → 126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam11235
    Location:137 → 298
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam13401
    Location:2036 → 2123
    AAA_22; AAA domain
    pfam15898
    Location:1790 → 1842
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

  2. NM_175272.3 → NP_780481.2  neuron navigator 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107862, AC119848, AK039374, AK040152, AK129480, BM936768, BQ964922, CF580688, CF584312, CF584313, CF742564, CF743819, CF744797, CK781037, DV652788
    Consensus CDS
    CCDS71973.1
    UniProtKB/TrEMBL
    V9GX91
    Related
    ENSMUSP00000139045.2, ENSMUST00000184945.8
    Conserved Domains (4) summary
    smart00382
    Location:2094 → 2202
    AAA; ATPases associated with a variety of cellular activities
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam13401
    Location:2097 → 2184
    AAA_22; AAA domain
    pfam15898
    Location:1851 → 1903
    PRKG1_interact; cGMP-dependent protein kinase interacting domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    48608796..49259838
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541300.5 → XP_006541363.1  neuron navigator 2 isoform X18

    Conserved Domains (6) summary
    PHA03307
    Location:891 → 1242
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:142 → 335
    PRK07003; DNA polymerase III subunit gamma/tau
    cd00014
    Location:22 → 126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1571 → 1842
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:249 → 643
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2031 → 2124
    AAA_22; AAA domain

  2. XM_036153585.1 → XP_036009478.1  neuron navigator 2 isoform X28

    Conserved Domains (6) summary
    PHA03307
    Location:890 → 1255
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:142 → 335
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1382 → 1654
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:249 → 643
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1842 → 1935
    AAA_22; AAA domain
    cd21285
    Location:15 → 127
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  3. XM_006541297.5 → XP_006541360.1  neuron navigator 2 isoform X14

    Conserved Domains (5) summary
    PHA03307
    Location:914 → 1265
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:22 → 126
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1594 → 1865
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:272 → 666
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2054 → 2147
    AAA_22; AAA domain

  4. XM_036153579.1 → XP_036009472.1  neuron navigator 2 isoform X23

    Conserved Domains (5) summary
    PHA03307
    Location:833 → 1184
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1513 → 1785
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:191 → 585
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1973 → 2066
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  5. XM_036153580.1 → XP_036009473.1  neuron navigator 2 isoform X24

    Conserved Domains (6) summary
    PHA03307
    Location:810 → 1161
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:61 → 254
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1490 → 1762
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:168 → 562
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1950 → 2043
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  6. XM_036153582.1 → XP_036009475.1  neuron navigator 2 isoform X25

    Conserved Domains (6) summary
    PHA03307
    Location:809 → 1160
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:61 → 254
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1489 → 1761
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:168 → 562
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1949 → 2042
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  7. XM_036153586.1 → XP_036009479.1  neuron navigator 2 isoform X31

    Conserved Domains (6) summary
    PHA03307
    Location:810 → 1175
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:61 → 254
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1302 → 1378
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:168 → 562
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1759 → 1852
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  8. XM_036153568.1 → XP_036009461.1  neuron navigator 2 isoform X1

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1342
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1671 → 1943
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2131 → 2224
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  9. XM_036153570.1 → XP_036009463.1  neuron navigator 2 isoform X3

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1342
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1671 → 1747
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2128 → 2221
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  10. XM_036153571.1 → XP_036009464.1  neuron navigator 2 isoform X4

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1342
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1656 → 1928
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2116 → 2209
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  11. XM_036153575.1 → XP_036009468.1  neuron navigator 2 isoform X10

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1342
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1634 → 1906
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2094 → 2187
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  12. XM_036153583.1 → XP_036009476.1  neuron navigator 2 isoform X26

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1356
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1483 → 1755
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1943 → 2036
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  13. XM_036153569.1 → XP_036009462.1  neuron navigator 2 isoform X2

    Conserved Domains (5) summary
    PHA03307
    Location:990 → 1341
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1670 → 1942
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2130 → 2223
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  14. XM_036153572.1 → XP_036009465.1  neuron navigator 2 isoform X7

    Conserved Domains (6) summary
    PHA03307
    Location:968 → 1319
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:219 → 412
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1648 → 1920
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:326 → 720
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2108 → 2201
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  15. XM_036153573.1 → XP_036009466.1  neuron navigator 2 isoform X8

    Conserved Domains (6) summary
    PHA03307
    Location:967 → 1318
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:219 → 412
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1647 → 1919
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:326 → 720
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2107 → 2200
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  16. XM_006541311.5 → XP_006541374.1  neuron navigator 2 isoform X41

    Conserved Domains (5) summary
    PHA03307
    Location:975 → 1326
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1688 → 1959
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:333 → 727
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2148 → 2241
    AAA_22; AAA domain

  17. XM_006541288.5 → XP_006541351.1  neuron navigator 2 isoform X5

    Conserved Domains (5) summary
    PHA03307
    Location:975 → 1326
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1655 → 1926
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:333 → 727
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2115 → 2208
    AAA_22; AAA domain

  18. XM_006541289.5 → XP_006541352.1  neuron navigator 2 isoform X6

    Conserved Domains (5) summary
    PHA03307
    Location:974 → 1325
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1654 → 1925
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:333 → 727
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2114 → 2207
    AAA_22; AAA domain

  19. XM_006541293.5 → XP_006541356.1  neuron navigator 2 isoform X11

    Conserved Domains (6) summary
    PHA03307
    Location:952 → 1303
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:203 → 396
    PRK07003; DNA polymerase III subunit gamma/tau
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1632 → 1903
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:310 → 704
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2092 → 2185
    AAA_22; AAA domain

  20. XM_036153576.1 → XP_036009469.1  neuron navigator 2 isoform X12

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1342
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1634 → 1710
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2091 → 2184
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  21. XM_036153584.1 → XP_036009477.1  neuron navigator 2 isoform X27

    Conserved Domains (5) summary
    PHA03307
    Location:991 → 1356
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1483 → 1559
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:349 → 743
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1940 → 2033
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  22. XM_036153574.1 → XP_036009467.1  neuron navigator 2 isoform X9

    Conserved Domains (6) summary
    PHA03307
    Location:968 → 1319
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:219 → 412
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1648 → 1724
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:326 → 720
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2105 → 2198
    AAA_22; AAA domain
    cd21285
    Location:74 → 204
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  23. XM_006541295.5 → XP_006541358.1  neuron navigator 2 isoform X13

    Conserved Domains (7) summary
    PHA03307
    Location:952 → 1303
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:203 → 396
    PRK07003; DNA polymerase III subunit gamma/tau
    cd00014
    Location:86 → 187
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR04523
    Location:1632 → 1708
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:310 → 704
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam15898
    Location:1849 → 1901
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam13401
    Location:2089 → 2182
    AAA_22; AAA domain

  24. XM_006541299.5 → XP_006541362.1  neuron navigator 2 isoform X16

    Conserved Domains (5) summary
    PHA03307
    Location:906 → 1257
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:15 → 118
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1586 → 1857
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:264 → 658
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2046 → 2139
    AAA_22; AAA domain

  25. XM_017312396.3 → XP_017167885.1  neuron navigator 2 isoform X20

    Conserved Domains (6) summary
    PHA03307
    Location:883 → 1234
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:134 → 327
    PRK07003; DNA polymerase III subunit gamma/tau
    cd00014
    Location:15 → 118
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1563 → 1834
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:241 → 635
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2023 → 2116
    AAA_22; AAA domain

  26. XM_036153581.1 → XP_036009474.1  neuron navigator 2 isoform X24

    Conserved Domains (6) summary
    PHA03307
    Location:810 → 1161
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:61 → 254
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1490 → 1762
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:168 → 562
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1950 → 2043
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  27. XM_017312397.3 → XP_017167886.1  neuron navigator 2 isoform X23

    Conserved Domains (5) summary
    PHA03307
    Location:833 → 1184
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1513 → 1785
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:191 → 585
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1973 → 2066
    AAA_22; AAA domain
    cl00030
    Location:1 → 46
    CH_SF; calponin homology (CH) domain superfamily

  28. XM_006541298.5 → XP_006541361.1  neuron navigator 2 isoform X15

    Conserved Domains (5) summary
    PHA03307
    Location:913 → 1264
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00014
    Location:23 → 125
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    TIGR02168
    Location:1593 → 1864
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:271 → 665
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2053 → 2146
    AAA_22; AAA domain

  29. XM_036153578.1 → XP_036009471.1  neuron navigator 2 isoform X19

    Conserved Domains (6) summary
    PHA03307
    Location:889 → 1240
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:141 → 334
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR04523
    Location:1569 → 1841
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:248 → 642
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2029 → 2122
    AAA_22; AAA domain
    cd21285
    Location:22 → 126
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  30. XM_036153577.1 → XP_036009470.1  neuron navigator 2 isoform X17

    Conserved Domains (5) summary
    PHA03307
    Location:897 → 1248
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:1577 → 1849
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam05109
    Location:255 → 649
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2037 → 2130
    AAA_22; AAA domain
    cd21285
    Location:1 → 110
    CH_NAV2; calponin homology (CH) domain found in neuron navigator 2

  31. XM_006541302.3 → XP_006541365.1  neuron navigator 2 isoform X21

    Conserved Domains (5) summary
    PHA03307
    Location:867 → 1218
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:1547 → 1818
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:225 → 619
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:2007 → 2100
    AAA_22; AAA domain
    cl00030
    Location:20 → 79
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

  32. XM_006541303.3 → XP_006541366.1  neuron navigator 2 isoform X22

    Conserved Domains (6) summary
    PHA03307
    Location:844 → 1195
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07003
    Location:95 → 288
    PRK07003; DNA polymerase III subunit gamma/tau
    TIGR02168
    Location:1524 → 1795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:202 → 596
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1984 → 2077
    AAA_22; AAA domain
    cl00030
    Location:20 → 79
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...

  33. XM_006541307.5 → XP_006541370.1  neuron navigator 2 isoform X30

    Conserved Domains (3) summary
    PHA03307
    Location:626 → 977
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:1306 → 1577
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1766 → 1859
    AAA_22; AAA domain

  34. XM_006541306.5 → XP_006541369.1  neuron navigator 2 isoform X29

    Conserved Domains (4) summary
    PHA03307
    Location:643 → 994
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:1323 → 1594
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05109
    Location:8 → 395
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13401
    Location:1783 → 1876
    AAA_22; AAA domain

  35. XM_006541308.5 → XP_006541371.1  neuron navigator 2 isoform X32

    Conserved Domains (3) summary
    PHA03307
    Location:63 → 414
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:743 → 1014
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1203 → 1296
    AAA_22; AAA domain

  36. XM_030243111.2 → XP_030098971.1  neuron navigator 2 isoform X32

    Conserved Domains (3) summary
    PHA03307
    Location:63 → 414
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:743 → 1014
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1203 → 1296
    AAA_22; AAA domain

  37. XM_006541309.5 → XP_006541372.1  neuron navigator 2 isoform X33

    Conserved Domains (3) summary
    PHA03307
    Location:33 → 384
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:713 → 984
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1173 → 1266
    AAA_22; AAA domain

  38. XM_030243113.1 → XP_030098973.1  neuron navigator 2 isoform X36

    Conserved Domains (4) summary
    PHA03307
    Location:32 → 383
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:675 → 751
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam15898
    Location:892 → 944
    PRKG1_interact; cGMP-dependent protein kinase interacting domain
    pfam13401
    Location:1132 → 1225
    AAA_22; AAA domain

  39. XM_006541310.5 → XP_006541373.1  neuron navigator 2 isoform X34

    Conserved Domains (3) summary
    PHA03307
    Location:32 → 383
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:712 → 983
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1172 → 1265
    AAA_22; AAA domain

  40. XM_030243112.2 → XP_030098972.1  neuron navigator 2 isoform X35

    Conserved Domains (3) summary
    PHA03307
    Location:32 → 383
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:675 → 946
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1135 → 1228
    AAA_22; AAA domain

  41. XM_030243115.2 → XP_030098975.1  neuron navigator 2 isoform X38

    Conserved Domains (3) summary
    PHA03307
    Location:32 → 397
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:524 → 795
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:984 → 1077
    AAA_22; AAA domain

  42. XM_036153587.1 → XP_036009480.1  neuron navigator 2 isoform X39

    Conserved Domains (3) summary
    PHA03307
    Location:32 → 397
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:524 → 600
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam13401
    Location:981 → 1074
    AAA_22; AAA domain

  43. XM_030243114.2 → XP_030098974.1  neuron navigator 2 isoform X37

    Conserved Domains (3) summary
    PHA03307
    Location:2 → 296
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR02168
    Location:625 → 896
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13401
    Location:1085 → 1178
    AAA_22; AAA domain

  44. XM_036153588.1 → XP_036009481.1  neuron navigator 2 isoform X40

    Conserved Domains (3) summary
    PHA03307
    Location:2 → 310
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:437 → 709
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    pfam13401
    Location:897 → 990
    AAA_22; AAA domain

RNA

  1. XR_004934220.1 RNA Sequence

  2. XR_004934221.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools