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MAST4 microtubule associated serine/threonine kinase family member 4 [ Bos taurus (domestic cattle) ]

Gene ID: 529061, updated on 10-Oct-2024

Summary

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Official Symbol
MAST4provided by VGNC
Official Full Name
microtubule associated serine/threonine kinase family member 4provided by VGNC
Primary source
VGNC:VGNC:58387
See related
Ensembl:ENSBTAG00000025964
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See MAST4 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (12442476..13060918, complement)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104975219 Neighboring gene CD180 molecule Neighboring gene uncharacterized LOC112442988 Neighboring gene microRNA mir-2285z Neighboring gene microRNA mir-2285q Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1 Neighboring gene erbb2 interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microtubule-associated serine/threonine-protein kinase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    12442476..13060918 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878864.1 → XP_059734847.1  microtubule-associated serine/threonine-protein kinase 4 isoform X6

  2. XM_024981445.2 → XP_024837213.1  microtubule-associated serine/threonine-protein kinase 4 isoform X4

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:1141 → 1217
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:562 → 841
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:251 → 524
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2241 → 2766
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1816 → 2240
    Atrophin-1; Atrophin-1 family

  3. XM_024981444.2 → XP_024837212.1  microtubule-associated serine/threonine-protein kinase 4 isoform X3

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:1153 → 1229
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:574 → 853
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:263 → 536
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2253 → 2778
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1828 → 2252
    Atrophin-1; Atrophin-1 family

  4. XM_059878862.1 → XP_059734845.1  microtubule-associated serine/threonine-protein kinase 4 isoform X2

  5. XM_059878863.1 → XP_059734846.1  microtubule-associated serine/threonine-protein kinase 4 isoform X5

  6. XM_059878861.1 → XP_059734844.1  microtubule-associated serine/threonine-protein kinase 4 isoform X1

  7. XM_024981448.2 → XP_024837216.1  microtubule-associated serine/threonine-protein kinase 4 isoform X8

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:959 → 1035
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:380 → 659
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:69 → 342
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2059 → 2584
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1634 → 2058
    Atrophin-1; Atrophin-1 family

  8. XM_024981450.2 → XP_024837218.1  microtubule-associated serine/threonine-protein kinase 4 isoform X10

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:947 → 1023
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:368 → 647
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:57 → 330
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2047 → 2572
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1622 → 2046
    Atrophin-1; Atrophin-1 family

  9. XM_024981447.2 → XP_024837215.1  microtubule-associated serine/threonine-protein kinase 4 isoform X7

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:966 → 1042
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:387 → 666
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:76 → 349
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2066 → 2591
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1641 → 2065
    Atrophin-1; Atrophin-1 family

  10. XM_024981454.2 → XP_024837222.1  microtubule-associated serine/threonine-protein kinase 4 isoform X12

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:887 → 963
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:375 → 654
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:64 → 337
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:1987 → 2512
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1562 → 1986
    Atrophin-1; Atrophin-1 family

  11. XM_024981449.2 → XP_024837217.1  microtubule-associated serine/threonine-protein kinase 4 isoform X9

    UniProtKB/TrEMBL
    E1BH93
    Related
    ENSBTAP00000036658.6, ENSBTAT00000036805.6
    Conserved Domains (5) summary
    cd00992
    Location:954 → 1030
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:375 → 654
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:64 → 337
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2054 → 2579
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1629 → 2053
    Atrophin-1; Atrophin-1 family

  12. XM_024981451.2 → XP_024837219.1  microtubule-associated serine/threonine-protein kinase 4 isoform X11

    UniProtKB/TrEMBL
    E1BH93
    Conserved Domains (5) summary
    cd00992
    Location:936 → 1012
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:357 → 636
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:46 → 319
    DUF1908; Domain of unknown function (DUF1908)
    cl25732
    Location:2036 → 2561
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26464
    Location:1611 → 2035
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
Heading Accession and Version

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