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Zfp2 zinc finger protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497897, updated on 17-Aug-2024

Summary

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Symbol
Zfp2provided by RGD
Full Name
zinc finger protein 2provided by RGD
Primary source
RGD:1562610
See related
EnsemblRapid:ENSRNOG00000030750 AllianceGenome:RGD:1562610
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mkr2; Mkr-2
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP2 (ZFP2 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 90.8), Kidney (RPKM 49.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp2 in Genome Data Viewer
Location:
10q22
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (35701303..35729861, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35209187..35228849, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (36388136..36406721, complement)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 6 Neighboring gene zinc finger protein 454 Neighboring gene zinc finger protein 354B Neighboring gene uncharacterized LOC134480687

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Mesa K, et al. Cancer Lett, 1996 Jun 5. PMID 8635150
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein ZFP2
Names
multifinger protein mKr2
zinc finger protein 2 homolog
zinc finger protein 879-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127558.1 → NP_001121030.1  zinc finger protein ZFP2

    See identical proteins and their annotated locations for NP_001121030.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161925
    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000110159.1, ENSRNOT00000158635.1
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    35701303..35729861 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269599.1 → XP_063125669.1  zinc finger protein ZFP2 isoform X2

  2. XM_063269601.1 → XP_063125671.1  zinc finger protein ZFP2 isoform X2

  3. XM_063269603.1 → XP_063125673.1  zinc finger protein ZFP2 isoform X2

  4. XM_063269602.1 → XP_063125672.1  zinc finger protein ZFP2 isoform X2

  5. XM_063269598.1 → XP_063125668.1  zinc finger protein ZFP2 isoform X2

  6. XM_063269600.1 → XP_063125670.1  zinc finger protein ZFP2 isoform X2

  7. XM_063269597.1 → XP_063125667.1  zinc finger protein ZFP2 isoform X2

  8. XM_039086551.1 → XP_038942479.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000108026.1, ENSRNOT00000121510.1
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  9. XM_039086549.2 → XP_038942477.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000102842.1, ENSRNOT00000144069.1
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  10. XM_039086558.1 → XP_038942486.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  11. XM_039086554.1 → XP_038942482.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  12. XM_039086556.1 → XP_038942484.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  13. XM_039086555.1 → XP_038942483.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000105741.1, ENSRNOT00000155915.1
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  14. XM_039086552.1 → XP_038942480.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000088741.1, ENSRNOT00000114612.2
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  15. XM_039086557.1 → XP_038942485.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  16. XM_039086553.1 → XP_038942481.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000041481.2, ENSRNOT00000040346.4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]

  17. XM_063269595.1 → XP_063125665.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Related
    ENSRNOP00000085038.1, ENSRNOT00000102165.2

  18. XM_039086550.2 → XP_038942478.1  zinc finger protein ZFP2 isoform X1

    UniProtKB/TrEMBL
    A0A8I6A0G2, B1WBX4
    Conserved Domains (2) summary
    COG5048
    Location:76 → 451
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:384 → 404
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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