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PPY pancreatic polypeptide [ Canis lupus familiaris (dog) ]

Gene ID: 490944, updated on 17-Aug-2024

Summary

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Official Symbol
PPYprovided by VGNC
Official Full Name
pancreatic polypeptideprovided by VGNC
Primary source
VGNC:VGNC:44933
See related
Ensembl:ENSCAFG00845009906
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
PP
Orthologs
human mouse all
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Genomic context

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See PPY in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (20089261..20090853)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (18784564..18785316)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (19271259..19272011)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (18943380..18944132)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (19126341..19127093)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 101 Neighboring gene N-acetylglutamate synthase Neighboring gene circumsporozoite protein Neighboring gene peptide YY Neighboring gene MAGUK p55 scaffold protein 2 Neighboring gene CD300 molecule like family member g

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cat pancreatic eicosapeptide and its biosynthetic intermediate. Conservation of a monobasic processing site. Nielsen HV, et al. Biochem J, 1986 Nov 15. PMID 3827854, Free PMC Article
  2. Canine pancreatic polypeptide complementary deoxyribonucleic acid sequence: pancreatic polypeptide and insulin messenger ribonucleic acid distribution in the lobes of the pancreas. Toothman P, et al. Mol Endocrinol, 1987 Jun. PMID 3079195
  3. Isolation and biogenesis of a new peptide from pancreatic islets. Schwartz TW, et al. Nature, 1981 Dec 10. PMID 7031480

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables neuropeptide Y receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuropeptide hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in feeding behavior IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pancreatic polypeptide prohormone; pancreatic prohormone

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001313876.2 → NP_001300805.1  pancreatic polypeptide prohormone precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAAUVH010000313
    UniProtKB/Swiss-Prot
    P01299
    UniProtKB/TrEMBL
    A0A8C0KHG2, A0A8C0M3N1, A0A8I3ND24
    Related
    ENSCAFP00845013563.1, ENSCAFT00845017420.1
    Conserved Domains (1) summary
    smart00309
    Location:30 → 65
    PAH; Pancreatic hormones / neuropeptide F / peptide YY family

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    20089261..20090853
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675051.1 → XP_038530979.1  pancreatic prohormone isoform X1

    UniProtKB/TrEMBL
    A0A8C0T0Q3
    Conserved Domains (1) summary
    smart00309
    Location:63 → 98
    PAH; Pancreatic hormones / neuropeptide F / peptide YY family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    18943380..18944132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    19126341..19127093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    19271259..19272011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    18784564..18785316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P01299.3 GenPept UniProtKB/Swiss-Prot:P01299

Gene LinkOut

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Molecular Biology Databases
Research Materials