FOXO1 forkhead box O1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: FOXO1provided by VGNC
Official Full Name: forkhead box O1provided by VGNC
Primary source: VGNC:VGNC:14510
Locus tag: CK820_G0019654
See related: Ensembl:ENSPTRG00000005806
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: FOXO1A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	14	NC_072412.2 (39654719..39765235, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	13	NC_072411.1 (34431553..34542039, complement)

Chromosome 14 - NC_072412.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

FOXO1A_111 (e-PCR)
- UniSTS:277254

RH78770 (e-PCR)
- UniSTS:59152

D13S1051 (e-PCR)
- UniSTS:152383

SHGC-82099 (e-PCR)
- UniSTS:103025

SHGC-63663 (e-PCR)
- UniSTS:47986

D13S1447 (e-PCR)
- UniSTS:37241

G64954 (e-PCR)
- UniSTS:164987

RH74854 (e-PCR)
- UniSTS:92039

PMC25098P1 (e-PCR)
- UniSTS:272280

RH93960 (e-PCR)
- UniSTS:88229

D13S1162 (e-PCR)
- UniSTS:78564

RH47740 (e-PCR)
- UniSTS:16884

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in insulin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: forkhead box protein O1

Names: forkhead box O1A; forkhead box protein O1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

39654719..39765235 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_522749.9 → XP_522749.3 forkhead box protein O1

See identical proteins and their annotated locations for XP_522749.3

UniProtKB/TrEMBL

A0A2J8MLD2, A0A6D2WMC7, H2Q7G4

Related

ENSPTRP00000009886.3

Conserved Domains (3) summary

cd00059
Location:160 → 240

FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

pfam16675
Location:423 → 500

FOXO_KIX_bdg; KIX-binding domain of forkhead box O, CR2

pfam16676
Location:597 → 633

FOXO-TAD; Transactivation domain of FOXO protein family