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INS insulin [ Pan troglodytes (chimpanzee) ]

Gene ID: 449570, updated on 17-Aug-2024

Summary

Official Symbol
INSprovided by VGNC
Official Full Name
insulinprovided by VGNC
Primary source
VGNC:VGNC:1070
See related
Ensembl:ENSPTRG00000003172
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See INS in Genome Data Viewer
Location:
chromosome: 9
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 9 NC_072407.2 (6426975..6428747, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) Unplaced Scaffold NW_026545376.1 (114368..116140, complement)

Chromosome 9 - NC_072407.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807287 Neighboring gene uncharacterized LOC134807324 Neighboring gene insulin like growth factor 2 Neighboring gene IGF2 antisense RNA Neighboring gene tyrosine hydroxylase Neighboring gene achaete-scute family bHLH transcription factor 2

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of protein secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
insulin
Names
preproinsulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008996.2NP_001008996.1  insulin preproprotein

    See identical proteins and their annotated locations for NP_001008996.1

    Status: VALIDATED

    Source sequence(s)
    X61089
    UniProtKB/Swiss-Prot
    P30410
    Related
    ENSPTRP00000005606.4, ENSPTRT00000006075.5
    Conserved Domains (1) summary
    cd04367
    Location:26110
    IlGF_insulin_like; IlGF_like family, insulin_like subgroup, specific to vertebrates. Members include a number of peptides including insulin and insulin-like growth factors I and II, which play a variety of roles in controlling processes such as metabolism, growth and ...

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    6426975..6428747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016919751.3XP_016775240.2  insulin isoform X1