AIFM1 apoptosis inducing factor, mitochondria associated 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: AIFM1provided by CGNC
Full Name: apoptosis inducing factor, mitochondria associated 1provided by CGNC
Primary source: CGNC:2941
See related: Ensembl:ENSGALG00010016598
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: PDCD8
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	4	NC_052535.1 (1532992..1544694)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	4	NC_052576.1 (1569494..1581196)

Chromosome 4 - NC_052535.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables FAD binding	IEA Inferred from Electronic Annotation more info	PubMed
enables NAD(P)H oxidase H2O2-forming activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mitochondrial respiratory chain complex assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apoptosis-inducing factor 1, mitochondrial

Names: apoptosis-inducing factor, mitochondrion-associated, 1; programmed cell death 8 (apoptosis-inducing factor)

NP_001007491.1

EC 1.1.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007490.2 → NP_001007491.1 apoptosis-inducing factor 1, mitochondrial

See identical proteins and their annotated locations for NP_001007491.1

Status: VALIDATED

Source sequence(s)

JAENSK010000071

UniProtKB/TrEMBL

A0A8V0YX07, F1P338, Q5ZHL7

Related

ENSGALP00010023180.1, ENSGALT00010040022.1

Conserved Domains (3) summary

pfam00070
Location:280 → 364

Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase

pfam07992
Location:128 → 425

Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase

pfam14721
Location:443 → 571

AIF_C; Apoptosis-inducing factor, mitochondrion-associated, C-term