MTF1 metal regulatory transcription factor 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: MTF1provided by CGNC
Full Name: metal regulatory transcription factor 1provided by CGNC
Primary source: CGNC:1142
See related: Ensembl:ENSGALG00010013274
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	23	NC_052554.1 (3910148..3928852)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	23	NC_052595.1 (3676667..3695359)

Chromosome 23 - NC_052554.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

24 h after imprinting, learning-related increases in MTF-1 and DRP-1 were observed bilaterally in the intermediate medial mesopallium, but not in either side of the posterior pole of the nidopallium. Cytoplasmic DRP-1 was not changed significantly in any region studied.
Title: Mitochondrial fusion and fission proteins and the recognition memory of imprinting in domestic chicks.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in central nervous system development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: metal regulatory transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031495.2 → NP_001026666.1 metal regulatory transcription factor 1

See identical proteins and their annotated locations for NP_001026666.1

Status: VALIDATED

Source sequence(s)

AJ455786, AJ455787, AJ719787, CD217759, JAENSK010000339

UniProtKB/TrEMBL

Q5ZLE7

Related

ENSGALP00010018709.1, ENSGALT00010031911.1

Conserved Domains (3) summary

COG5048
Location:148 → 292

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:235 → 254

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:246 → 272

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052554.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

3910148..3928852

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040651733.2 → XP_040507667.1 metal regulatory transcription factor 1 isoform X1

Conserved Domains (2) summary

COG5048
Location:148 → 292

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:235 → 254

ZF_C2H2; C2H2 Zn finger [structural motif]
XM_015297695.4 → XP_015153181.1 metal regulatory transcription factor 1 isoform X2

UniProtKB/TrEMBL

Q5ZLE7

Conserved Domains (3) summary

COG5048
Location:148 → 292

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:235 → 254

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:246 → 272

zf-H2C2_2; Zinc-finger double domain
XM_040651732.2 → XP_040507666.1 metal regulatory transcription factor 1 isoform X1

Conserved Domains (2) summary

COG5048
Location:148 → 292

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:235 → 254

ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052595.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

3676667..3695359

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046932026.1 → XP_046787982.1 metal regulatory transcription factor 1 isoform X1
XM_046932027.1 → XP_046787983.1 metal regulatory transcription factor 1 isoform X2

UniProtKB/TrEMBL

Q5ZLE7
XM_046932025.1 → XP_046787981.1 metal regulatory transcription factor 1 isoform X1