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rxrb.S retinoid X receptor beta S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398075, updated on 4-Nov-2024

Summary

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Official Symbol
rxrb.S
Official Full Name
retinoid X receptor beta S homeolog
Primary source
Xenbase:XB-GENE-865350
Locus tag
XELAEV_18042424mg
See related
EnsemblRapid:ENSXLAG00005009813 AllianceGenome:Xenbase:XB-GENE-865350
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rxrb; rxrb-a; rxrb-b; RXRbeta
Summary
Predicted to enable nuclear steroid receptor activity; retinoic acid-responsive element binding activity; and zinc ion binding activity. Predicted to act upstream of or within several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to be located in nucleus. Orthologous to human RXRB (retinoid X receptor beta). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rxrb.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (80621950..80639140)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (78241217..78258420)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 22 S homeolog Neighboring gene uncharacterized LOC100126628 Neighboring gene collagen type XI alpha 2 S homeolog Neighboring gene bromodomain containing 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of a novel RXR from Xenopus that most closely resembles mammalian RXR beta and is expressed throughout early development. Marklew S, et al. Biochim Biophys Acta, 1994 Aug 2. PMID 8049252
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables retinoic acid-responsive element binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to retinoic acid IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within retinoic acid receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
retinoid X receptor beta S homeolog
Names
retinoid X receptor, beta
xRXR beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088361.1 → NP_001081830.1  retinoid X receptor beta S homeolog

    See identical proteins and their annotated locations for NP_001081830.1

    Status: PROVISIONAL

    Source sequence(s)
    S73269
    UniProtKB/TrEMBL
    A0A974H6H2, Q6INZ0, Q91613
    Related
    ENSXLAP00005028795.1, ENSXLAT00005029535.1
    Conserved Domains (3) summary
    cd06943
    Location:221 → 430
    NR_LBD_RXR_like; The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily
    cd06956
    Location:127 → 202
    NR_DBD_RXR; DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers
    pfam11825
    Location:13 → 120
    Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    80621950..80639140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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