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nr2f6.L nuclear receptor subfamily 2 group F member 6 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379873, updated on 4-Nov-2024

Summary

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Official Symbol
nr2f6.L
Official Full Name
nuclear receptor subfamily 2 group F member 6 L homeolog
Primary source
Xenbase:XB-GENE-480822
Locus tag
XELAEV_18006580mg
See related
EnsemblRapid:ENSXLAG00005028577 AllianceGenome:Xenbase:XB-GENE-480822
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ear2; ear-2; nr2f6; erbal2
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and zinc ion binding activity. Predicted to act upstream of or within cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human NR2F6 (nuclear receptor subfamily 2 group F member 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nr2f6.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (121430151..121452395, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (109163003..109186664, complement)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene occludin/ELL domain containing 1 L homeolog Neighboring gene occludin/ELL domain containing 1 gene 2 L homeolog Neighboring gene BRISC and BRCA1 A complex member 1 L homeolog Neighboring gene speedy protein 1-B-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC69000

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nuclear receptor subfamily 2 group F member 6 L homeolog
Names
nuclear receptor subfamily 2, group F, member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086712.1 → NP_001080181.1  nuclear receptor subfamily 2 group F member 6 L homeolog

    See identical proteins and their annotated locations for NP_001080181.1

    Status: PROVISIONAL

    Source sequence(s)
    BC056043
    UniProtKB/TrEMBL
    A0A974DZ43, Q7T0T7
    Related
    ENSXLAP00005085045.1, ENSXLAT00005086706.1
    Conserved Domains (2) summary
    cd06948
    Location:152 → 388
    NR_LBD_COUP-TF; Ligand binding domain of chicken ovalbumin upstream promoter transcription factors, a member of the nuclear receptor family
    cd06958
    Location:54 → 126
    NR_DBD_COUP_TF; DNA-binding domain of chicken ovalbumin upstream promoter transcription factors (COUP-TFs) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    121430151..121452395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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