GRPR gastrin releasing peptide receptor [Gallus gallus (chicken)] - Gene

Summary

Symbol: GRPRprovided by CGNC
Full Name: gastrin releasing peptide receptorprovided by CGNC
Primary source: CGNC:66191
See related: Ensembl:ENSGALG00010001488
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (121815141..121837881, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (121805166..121827905, complement)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Gastrin-releasing peptide receptor[chGRP-R] and chBRS-3.5 mRNA occurred in brain regions similar to those of mammals that express GRP-R. BN/GRP-immunoreactive neurons were found mainly in the pallium, a distribution like that of chBRS-3.5 mRNA
Title: Distributions of two chicken bombesin receptors, bombesin receptor subtype-3.5 (chBRS-3.5) and gastrin-releasing peptide receptor (chGRP-R) mRNAS in the chicken telencephalon.
Expression of GRP-R is detected in chick brain and gastrointestinal tissues; when expressed in Chinese hamster ovary K1 cells, GRP-R mediates intracellular calcium mobilization upon agonist stimulation.
Title: Molecular cloning and characterization of avian bombesin-like peptide receptors: new tools for investigating molecular basis for ligand selectivity.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled peptide receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: gastrin-releasing peptide receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204407.2 → NP_989738.1 gastrin-releasing peptide receptor

See identical proteins and their annotated locations for NP_989738.1

Status: VALIDATED

Source sequence(s)

JAENSK010000022

UniProtKB/TrEMBL

Q802E7

Related

ENSGALP00010001884.1, ENSGALT00010003441.1

Conserved Domains (1) summary

pfam00001
Location:64 → 322

7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

121815141..121837881 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

121805166..121827905 complement

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GenBank, FASTA, Sequence Viewer (Graphics)