pgr.S progesterone receptor S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

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Official Symbol: pgr.S
Official Full Name: progesterone receptor S homeolog
Primary source: Xenbase:XB-GENE-6252885
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: pgr; ipgr; XPR-1; XPR-2; pgr-a; pgr-b; pr2-A
Annotation information: not in current annotation release
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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results suggest that the dual functions of progesterone, transcription-dependent follicle rupture and transcription-independent oocyte maturation, are mediated by the two forms of PR proteins differentially expressed in the follicle cells and the oocytes
Title: Transcription-dependent and transcription-independent functions of the classical progesterone receptor in Xenopus ovaries.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables estrogen response element binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info
enables nuclear steroid receptor activity	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables steroid binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nuclear receptor-mediated steroid hormone signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within steroid hormone receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: progesterone receptor S homeolog

Names: oviduct progesterone receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001085627.1 → NP_001079096.1 progesterone receptor S homeolog

See identical proteins and their annotated locations for NP_001079096.1

Status: PROVISIONAL

Source sequence(s)

AY007198

UniProtKB/TrEMBL

Q8UVY3, Q9DEV4

Conserved Domains (2) summary

cd07074
Location:336 → 583

NR_LBD_PR; Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor

cd07172
Location:212 → 289

NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers