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Gypc glycophorin C [ Rattus norvegicus (Norway rat) ]

Gene ID: 364837, updated on 14-Nov-2024

Summary

Official Symbol
Gypcprovided by RGD
Official Full Name
glycophorin Cprovided by RGD
Primary source
RGD:1310295
See related
AllianceGenome:RGD:1310295
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
GPC
Summary
Predicted to be located in plasma membrane. Predicted to be active in cortical cytoskeleton and membrane. Human ortholog(s) of this gene implicated in malaria. Orthologous to human GYPC (glycophorin C (Gerbich blood group)). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 104.3), Heart (RPKM 80.0) and 7 other tissues See more
Orthologs
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Genomic context

See Gypc in Genome Data Viewer
Location:
18p12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (24434921..24467592, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (24160738..24193408, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (25312386..25344614, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene POTE ankyrin domain family, member F Neighboring gene bridging integrator 1 Neighboring gene uncharacterized LOC120098229 Neighboring gene testis expressed 51 Neighboring gene uncharacterized LOC120098297 Neighboring gene uncharacterized LOC120098296 Neighboring gene large ribosomal subunit protein eL19-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC124900

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in cortical cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cortical cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glycophorin-C
Names
glycophorin C (Gerbich blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013233.1NP_001013251.1  glycophorin-C

    See identical proteins and their annotated locations for NP_001013251.1

    Status: PROVISIONAL

    Source sequence(s)
    AY234182
    UniProtKB/Swiss-Prot
    Q6XFR6
    UniProtKB/TrEMBL
    A0A8I5ZMD3
    Conserved Domains (1) summary
    smart00294
    Location:4765
    4.1m; putative band 4.1 homologues' binding motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    24434921..24467592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)