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Rnf182 ring finger protein 182 [ Mus musculus (house mouse) ]

Gene ID: 328234, updated on 2-Nov-2024

Summary

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Official Symbol
Rnf182provided by MGI
Official Full Name
ring finger protein 182provided by MGI
Primary source
MGI:MGI:3045355
See related
Ensembl:ENSMUSG00000044164 AllianceGenome:MGI:3045355
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C630023L15Rik
Summary
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in cortical plate; olfactory epithelium; rest of cerebellum mantle layer; and telencephalon marginal layer. Orthologous to human RNF182 (ring finger protein 182). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 7.8), whole brain E14.5 (RPKM 6.5) and 8 other tissues See more
Orthologs
human all
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Genomic context

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See Rnf182 in Genome Data Viewer
Location:
13 A4; 13 21.6 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (43769051..43824422)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (43615733..43670946)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32939 Neighboring gene mitochondrial calcium uniporter regulator 1 Neighboring gene STARR-seq mESC enhancer starr_34344 Neighboring gene STARR-seq mESC enhancer starr_34345 Neighboring gene predicted gene, 52070 Neighboring gene STARR-seq mESC enhancer starr_34346 Neighboring gene predicted gene, 20751

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Clone Names

  • MGC107143

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
  
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in protein ubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF182
Names
RING-type E3 ubiquitin transferase RNF182
NP_899027.1
XP_006516996.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183204.4 → NP_899027.1  E3 ubiquitin-protein ligase RNF182

    See identical proteins and their annotated locations for NP_899027.1

    Status: VALIDATED

    Source sequence(s)
    AC124171, AC124465
    Consensus CDS
    CCDS26480.1
    UniProtKB/Swiss-Prot
    Q8C432
    Related
    ENSMUSP00000062005.3, ENSMUST00000059986.3
    Conserved Domains (1) summary
    cd16555
    Location:19 → 69
    RING-HC_RNF182; RING finger, HC subclass, found in RING finger protein 182 (RNF182) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    43769051..43824422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516933.5 → XP_006516996.1  E3 ubiquitin-protein ligase RNF182 isoform X1

    See identical proteins and their annotated locations for XP_006516996.1

    UniProtKB/Swiss-Prot
    Q8C432
    Conserved Domains (1) summary
    cd16555
    Location:19 → 69
    RING-HC_RNF182; RING finger, HC subclass, found in RING finger protein 182 (RNF182) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C432.1 GenPept UniProtKB/Swiss-Prot:Q8C432

Gene LinkOut

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