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Ptprd protein tyrosine phosphatase, receptor type, D [ Rattus norvegicus (Norway rat) ]

Gene ID: 313278, updated on 2-Nov-2024

Summary

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Symbol
Ptprdprovided by RGD
Full Name
protein tyrosine phosphatase, receptor type, Dprovided by RGD
Primary source
RGD:1561090
See related
EnsemblRapid:ENSRNOG00000005711 AllianceGenome:RGD:1561090
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cell adhesion molecule binding activity; protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; regulation of postsynaptic density assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse. Biomarker of restless legs syndrome. Human ortholog(s) of this gene implicated in coronary artery disease; diabetes mellitus; hypertension; and type 2 diabetes mellitus. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 355.8), Kidney (RPKM 349.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ptprd in Genome Data Viewer
Location:
5q31
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (95093221..97415498, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (90046993..90698977, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (92862229..93514071, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486942 Neighboring gene eukaryotic translation elongation factor 1 gamma, pseudogene 16 Neighboring gene malate dehydrogenase 2, pseudogene 1 Neighboring gene uncharacterized LOC134486943 Neighboring gene U6 spliceosomal RNA Neighboring gene component of oligomeric golgi complex 5, pseudogene 1 Neighboring gene uncharacterized LOC120103065 Neighboring gene developmentally regulated GTP binding protein 1, pseudogene 2 Neighboring gene uncharacterized LOC134486944 Neighboring gene zinc finger CCHC-type containing 9, pseudogene 3 Neighboring gene protein tyrosine phosphatase, receptor type, D like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Protein tyrosine phosphatase receptor type delta (PTPRD) gene in an animal model of restless legs syndrome. Morais MA, et al. J Sleep Res, 2023 Apr. PMID 36053904
  2. Effectiveness of exercise and pramipexole in the treatment of restless leg syndrome: Implications on the dopaminergic system and PTPRD. Morais MA, et al. Sleep Med, 2023 Oct. PMID 37633178
  3. Genome-wide association analysis of common genetic variants of resistant hypertension. El Rouby N, et al. Pharmacogenomics J, 2019 Jun. PMID 30237584, Free PMC Article
  4. Large scale association analysis identifies three susceptibility loci for coronary artery disease. Saade S, et al. PLoS One, 2011. PMID 22216278, Free PMC Article
  5. Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice. Uetani N, et al. EMBO J, 2000 Jun 15. PMID 10856223, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Protein tyrosine phosphatase receptor type delta (PTPRD) gene in an animal model of restless legs syndrome.
    Title: Protein tyrosine phosphatase receptor type delta (PTPRD) gene in an animal model of restless legs syndrome.
  2. Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCgamma1 axis.
    Title: Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis.
  3. Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.
    Title: Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cell adhesion molecule binding ISO
Inferred from Sequence Orthology
more info
  
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular response to platelet-derived growth factor stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISO
Inferred from Sequence Orthology
more info
  
involved_in modulation of chemical synaptic transmission ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within negative regulation of receptor signaling pathway via JAK-STAT ISO
Inferred from Sequence Orthology
more info
  
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in neuron differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of dendritic spine morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of synapse assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in presynapse assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in presynaptic membrane assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of immune response ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of postsynaptic density assembly EXP
Inferred from Experiment
more info
 PubMed 
involved_in regulation of postsynaptic density assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of postsynaptic density assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synaptic membrane adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synaptic membrane adhesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in synaptic membrane adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptic membrane adhesion ISO
Inferred from Sequence Orthology
more info
  
involved_in trans-synaptic signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in trans-synaptic signaling by trans-synaptic complex ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in Schaffer collateral - CA1 synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in glutamatergic synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
  
is_active_in presynaptic membrane ISO
Inferred from Sequence Orthology
more info
  
located_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase delta
XP_038967365.1
XP_038967368.1
XP_038967379.1
XP_038967381.1
XP_038967383.1
XP_038967384.1
XP_038967387.1
XP_038967389.1
XP_038967390.1
XP_038967391.1
XP_063144608.1
XP_063144609.1
XP_063144610.1
XP_063144611.1
XP_063144612.1
XP_063144613.1
XP_063144614.1
XP_063144615.1
XP_063144616.1
XP_063144617.1
XP_063144618.1
XP_063144619.1
XP_063144620.1
XP_063144621.1
XP_063144622.1
XP_063144623.1
XP_063144624.1
XP_063144625.1
XP_063144626.1
XP_063144627.1
XP_063144629.1
XP_063144630.1
XP_063144631.1
XP_063144632.1
XP_063144634.1
XP_063144635.1
XP_063144636.1
XP_063144637.1
XP_063144638.1
XP_063144639.1
XP_063144640.1
XP_063144641.1
XP_063144642.1
XP_063144643.1
XP_063144644.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427220.1 → NP_001414149.1  receptor-type tyrosine-protein phosphatase delta precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    95093221..97415498 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288539.1 → XP_063144609.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  2. XM_063288540.1 → XP_063144610.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  3. XM_039111462.2 → XP_038967390.1  receptor-type tyrosine-protein phosphatase delta isoform X42

    UniProtKB/TrEMBL
    A0A8I6A789
    Conserved Domains (8) summary
    cd00063
    Location:317 → 406
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:916 → 1199
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1200 → 1491
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    pfam18861
    Location:783 → 875
    PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 224
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:233 → 314
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  4. XM_039111461.2 → XP_038967389.1  receptor-type tyrosine-protein phosphatase delta isoform X40

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (8) summary
    cd00063
    Location:317 → 406
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:920 → 1203
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1204 → 1495
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    pfam18861
    Location:783 → 875
    PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 224
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:233 → 314
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  5. XM_063288574.1 → XP_063144644.1  receptor-type tyrosine-protein phosphatase delta isoform X41

  6. XM_063288566.1 → XP_063144636.1  receptor-type tyrosine-protein phosphatase delta isoform X27

  7. XM_063288565.1 → XP_063144635.1  receptor-type tyrosine-protein phosphatase delta isoform X26

  8. XM_063288564.1 → XP_063144634.1  receptor-type tyrosine-protein phosphatase delta isoform X25

  9. XM_063288559.1 → XP_063144629.1  receptor-type tyrosine-protein phosphatase delta isoform X21

    Related
    ENSRNOP00000089430.3, ENSRNOT00000094348.3

  10. XM_039111440.2 → XP_038967368.1  receptor-type tyrosine-protein phosphatase delta isoform X20

    UniProtKB/TrEMBL
    A0A8I6AEM0
    Conserved Domains (8) summary
    cd00063
    Location:317 → 406
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:1322 → 1605
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1606 → 1897
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    pfam18861
    Location:1185 → 1277
    PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 224
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:233 → 314
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  11. XM_063288554.1 → XP_063144624.1  receptor-type tyrosine-protein phosphatase delta isoform X16

  12. XM_063288553.1 → XP_063144623.1  receptor-type tyrosine-protein phosphatase delta isoform X15

  13. XM_063288556.1 → XP_063144626.1  receptor-type tyrosine-protein phosphatase delta isoform X18

    Related
    ENSRNOP00000086806.3, ENSRNOT00000113220.3

  14. XM_063288550.1 → XP_063144620.1  receptor-type tyrosine-protein phosphatase delta isoform X11

  15. XM_039111459.2 → XP_038967387.1  receptor-type tyrosine-protein phosphatase delta isoform X39

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (8) summary
    cd00063
    Location:321 → 410
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:924 → 1207
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1208 → 1499
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    pfam18861
    Location:787 → 879
    PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 224
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:237 → 318
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  16. XM_063288548.1 → XP_063144618.1  receptor-type tyrosine-protein phosphatase delta isoform X9

  17. XM_063288562.1 → XP_063144632.1  receptor-type tyrosine-protein phosphatase delta isoform X24

  18. XM_039111453.2 → XP_038967381.1  receptor-type tyrosine-protein phosphatase delta isoform X34

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (7) summary
    cd00063
    Location:327 → 416
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:931 → 1214
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1215 → 1506
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 230
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:243 → 324
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  19. XM_039111456.2 → XP_038967384.1  receptor-type tyrosine-protein phosphatase delta isoform X37

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (7) summary
    cd00063
    Location:327 → 416
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:928 → 1211
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1212 → 1503
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 230
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:243 → 324
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  20. XM_063288561.1 → XP_063144631.1  receptor-type tyrosine-protein phosphatase delta isoform X23

  21. XM_063288544.1 → XP_063144614.1  receptor-type tyrosine-protein phosphatase delta isoform X5

  22. XM_063288571.1 → XP_063144641.1  receptor-type tyrosine-protein phosphatase delta isoform X32

    Related
    ENSRNOP00000098524.2, ENSRNOT00000120941.2

  23. XM_063288573.1 → XP_063144643.1  receptor-type tyrosine-protein phosphatase delta isoform X38

  24. XM_063288557.1 → XP_063144627.1  receptor-type tyrosine-protein phosphatase delta isoform X19

  25. XM_063288546.1 → XP_063144616.1  receptor-type tyrosine-protein phosphatase delta isoform X7

  26. XM_039111455.2 → XP_038967383.1  receptor-type tyrosine-protein phosphatase delta isoform X36

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (7) summary
    cd00063
    Location:330 → 419
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:930 → 1213
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1214 → 1505
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 233
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:246 → 327
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  27. XM_063288570.1 → XP_063144640.1  receptor-type tyrosine-protein phosphatase delta isoform X31

  28. XM_039111451.2 → XP_038967379.1  receptor-type tyrosine-protein phosphatase delta isoform X33

    UniProtKB/TrEMBL
    A0A8I5ZQN2
    Conserved Domains (7) summary
    cd00063
    Location:330 → 419
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:934 → 1217
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1218 → 1509
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 233
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:246 → 327
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  29. XM_063288568.1 → XP_063144638.1  receptor-type tyrosine-protein phosphatase delta isoform X29

  30. XM_063288572.1 → XP_063144642.1  receptor-type tyrosine-protein phosphatase delta isoform X35

  31. XM_063288569.1 → XP_063144639.1  receptor-type tyrosine-protein phosphatase delta isoform X30

  32. XM_063288567.1 → XP_063144637.1  receptor-type tyrosine-protein phosphatase delta isoform X28

  33. XM_063288560.1 → XP_063144630.1  receptor-type tyrosine-protein phosphatase delta isoform X22

  34. XM_063288555.1 → XP_063144625.1  receptor-type tyrosine-protein phosphatase delta isoform X17

  35. XM_063288549.1 → XP_063144619.1  receptor-type tyrosine-protein phosphatase delta isoform X10

  36. XM_063288547.1 → XP_063144617.1  receptor-type tyrosine-protein phosphatase delta isoform X8

  37. XM_039111463.2 → XP_038967391.1  receptor-type tyrosine-protein phosphatase delta isoform X4

    UniProtKB/TrEMBL
    A0A8I6A6R5
    Conserved Domains (9) summary
    cd00063
    Location:330 → 419
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:1358 → 1641
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1642 → 1933
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam00041
    Location:720 → 819
    fn3; Fibronectin type III domain
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    pfam18861
    Location:1207 → 1299
    PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 233
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:246 → 327
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  38. XM_039111437.2 → XP_038967365.1  receptor-type tyrosine-protein phosphatase delta isoform X14

    UniProtKB/TrEMBL
    A0A8I6A1V1
    Conserved Domains (8) summary
    cd00063
    Location:330 → 419
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14624
    Location:1341 → 1624
    R-PTPc-D-1; catalytic domain of receptor-type tyrosine-protein phosphatase D, repeat 1
    cd14628
    Location:1625 → 1916
    R-PTP-D-2; PTP-like domain of receptor-type tyrosine-protein phosphatase D, repeat 2
    pfam00041
    Location:720 → 819
    fn3; Fibronectin type III domain
    pfam07679
    Location:31 → 122
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:39 → 43
    Ig; Ig strand A' [structural motif]
    cd05738
    Location:134 → 233
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:246 → 327
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  39. XM_063288542.1 → XP_063144612.1  receptor-type tyrosine-protein phosphatase delta isoform X2

  40. XM_063288543.1 → XP_063144613.1  receptor-type tyrosine-protein phosphatase delta isoform X3

  41. XM_063288552.1 → XP_063144622.1  receptor-type tyrosine-protein phosphatase delta isoform X13

  42. XM_063288545.1 → XP_063144615.1  receptor-type tyrosine-protein phosphatase delta isoform X6

  43. XM_063288551.1 → XP_063144621.1  receptor-type tyrosine-protein phosphatase delta isoform X12

  44. XM_063288538.1 → XP_063144608.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  45. XM_063288541.1 → XP_063144611.1  receptor-type tyrosine-protein phosphatase delta isoform X1

    Related
    ENSRNOP00000091521.3, ENSRNOT00000119354.3
Nucleotide Protein Strain
Heading Accession and Version

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