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Cntnap5b contactin associated protein family member 5B [ Rattus norvegicus (Norway rat) ]

Gene ID: 301650, updated on 14-Nov-2024

Summary

Official Symbol
Cntnap5bprovided by RGD
Official Full Name
contactin associated protein family member 5Bprovided by RGD
Primary source
RGD:1565194
See related
EnsemblRapid:ENSRNOG00000064462 AllianceGenome:RGD:1565194
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Caspr5-2; Caspr5-3; Cntnap5c; RGD1565194
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in basement membrane and membrane. Orthologous to human CNTNAP5 (contactin associated protein family member 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 44.9) See more
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Genomic context

See Cntnap5b in Genome Data Viewer
Location:
13p12
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (18378255..19281711)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (17863367..18766983)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (21678088..22591082)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C14, pseudogene 1 Neighboring gene gem (nuclear organelle) associated protein 8, pseudogene 4 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14B like 1 Neighboring gene high mobility group box 3, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
contactin-associated protein like 5-2
Names
Cell recognition molecule Caspr5-2
Cell recognition molecule Caspr5b
Contactin-associated protein-like 5b
cell recognition molecule Caspr5-3
cell recognition molecule Caspr5c
contactin associated protein-like 5-2
contactin associated protein-like 5B
contactin-associated protein like 5-3
contactin-associated protein-like 5c

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001047873.2NP_001041338.2  contactin-associated protein like 5-2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/Swiss-Prot
    Q0V8T4
    Related
    ENSRNOP00000109197.1, ENSRNOT00000173948.1
    Conserved Domains (4) summary
    smart00282
    Location:10401172
    LamG; Laminin G domain
    cd00054
    Location:961996
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:63173
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:793937
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    18378255..19281711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063272213.1XP_063128283.1  contactin-associated protein like 5-2 isoform X3

    Related
    ENSRNOP00000103911.1, ENSRNOT00000166291.1
  2. XM_063272212.1XP_063128282.1  contactin-associated protein like 5-2 isoform X2

  3. XM_017598777.3XP_017454266.1  contactin-associated protein like 5-2 isoform X1

    UniProtKB/Swiss-Prot
    Q0V8T4
    Related
    ENSRNOP00000104116.1, ENSRNOT00000170064.1
  4. XM_017598779.3XP_017454268.1  contactin-associated protein like 5-2 isoform X4

    UniProtKB/Swiss-Prot
    Q0V8T4
  5. XM_063272214.1XP_063128284.1  contactin-associated protein like 5-2 isoform X5