Eif4b eukaryotic translation initiation factor 4B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Eif4bprovided by RGD
Official Full Name: eukaryotic translation initiation factor 4Bprovided by RGD
Primary source: RGD:1306479
See related: EnsemblRapid:ENSRNOG00000077907 AllianceGenome:RGD:1306479
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable RNA binding activity. Located in dendrite and neuronal cell body. Orthologous to human EIF4B (eukaryotic translation initiation factor 4B). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Thymus (RPKM 843.3), Muscle (RPKM 839.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q36

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (135085259..135107054)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (133206637..133228436)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (143679656..143701452)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH128420 (e-PCR)
- UniSTS:211728

RH137009 (e-PCR)
- UniSTS:219098

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: eukaryotic translation initiation factor 4B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008324.2 → NP_001008325.1 eukaryotic translation initiation factor 4B

See identical proteins and their annotated locations for NP_001008325.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

Q5RKG9

Related

ENSRNOP00000014033.6, ENSRNOT00000014033.7

Conserved Domains (2) summary

COG0724
Location:83 → 190

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12402
Location:95 → 171

RRM_eIF4B; RNA recognition motif in eukaryotic translation initiation factor 4B (eIF-4B) and similar proteins