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Cd69 Cd69 molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 29187, updated on 2-Nov-2024

Summary

Official Symbol
Cd69provided by RGD
Official Full Name
Cd69 moleculeprovided by RGD
Primary source
RGD:61318
See related
EnsemblRapid:ENSRNOG00000056783 AllianceGenome:RGD:61318
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables calcium ion binding activity. Predicted to be involved in cellular response to xenobiotic stimulus; negative regulation of T cell migration; and negative regulation of T-helper 17 cell lineage commitment. Predicted to be located in cell surface. Predicted to be part of protein-containing complex. Predicted to be active in external side of plasma membrane. Orthologous to human CD69 (CD69 molecule). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 246.4), Spleen (RPKM 80.1) and 2 other tissues See more
Orthologs
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Genomic context

See Cd69 in Genome Data Viewer
Location:
4q42
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (164411485..164419403, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (162725446..162733364, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163041147..163049065, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 2, member G Neighboring gene uncharacterized LOC100909928 Neighboring gene C-type lectin domain family 2, member M Neighboring gene C-type lectin domain family 12, member A Neighboring gene chromatin target of PRMT1-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular sequestering activity ISO
Inferred from Sequence Orthology
more info
 
enables transmembrane signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
C-type lectin domain family 2 member A
Names
CD69 antigen
early activation antigen CD69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134327.2NP_599154.1  C-type lectin domain family 2 member A

    See identical proteins and their annotated locations for NP_599154.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    A0A8I6G1Q9, D9Z4I9, Q5M851
    Related
    ENSRNOP00000105129.1, ENSRNOT00000153540.1
    Conserved Domains (1) summary
    cd03593
    Location:85196
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    164411485..164419403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)