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GRM8 glutamate metabotropic receptor 8 [ Homo sapiens (human) ]

Gene ID: 2918, updated on 2-Nov-2024

Summary

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Official Symbol
GRM8provided by HGNC
Official Full Name
glutamate metabotropic receptor 8provided by HGNC
Primary source
HGNC:HGNC:4600
See related
Ensembl:ENSG00000179603 MIM:601116; AllianceGenome:HGNC:4600
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLUR8; mGlu8; GPRC1H; MGLUR8
Summary
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Expression
Biased expression in brain (RPKM 1.2), testis (RPKM 1.0) and 9 other tissues See more
Orthologs
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Genomic context

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See GRM8 in Genome Data Viewer
Location:
7q31.33
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (126438598..127252941, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (127750296..128564614, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (126078652..126892995, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375487 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:125549855-125550449 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:125555064-125555651 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:125555652-125556238 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:125563618-125564252 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26574 Neighboring gene uncharacterized LOC105375488 Neighboring gene uncharacterized LOC101928357 Neighboring gene poly(A) binding protein cytoplasmic 4 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:126214200-126215399 Neighboring gene uncharacterized LOC107986843 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26575 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26576 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26577 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26578 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:126340799-126341998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26580 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26581 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:126418019-126418567 Neighboring gene uncharacterized LOC124901742 Neighboring gene microRNA 592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26582 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18590 Neighboring gene GRM8 antisense RNA 1 Neighboring gene PRELI domain containing 3B pseudogene 10 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18591 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:127032217-127032717 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18593 Neighboring gene zinc finger protein 800

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task. Bauer LO, et al. Clin Neurophysiol, 2020 Jun. PMID 32299001, Free PMC Article
  2. Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. Chen AC, et al. Am J Med Genet B Neuropsychiatr Genet, 2009 Apr 5. PMID 18618593, Free PMC Article
  3. Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8. Malherbe P, et al. Brain Res Mol Brain Res, 1999 Apr 20. PMID 10216218
  4. Glutamate acts as a partial inverse agonist to metabotropic glutamate receptor with a single amino acid mutation in the transmembrane domain. Yanagawa M, et al. J Biol Chem, 2013 Apr 5. PMID 23420844, Free PMC Article
  5. The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1. Scherer SW, et al. Genomics, 1997 Sep 1. PMID 9299241

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Association between the group III metabotropic glutamate receptor gene polymorphisms and attention-deficit/hyperactivity disorder and functional exploration of risk loci.
    Title: Association between the group III metabotropic glutamate receptor gene polymorphisms and attention-deficit/hyperactivity disorder and functional exploration of risk loci.
  2. GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.
    Title: GRM8 genotype is associated with externalizing disorders and greater inter-trial variability in brain activation during a response inhibition task.
  3. Transcriptional activation of GRM8 lung squamous cell carcinoma tumor cells induced cell proliferation by inhibiting cAMP pathway and activating MAPK pathway.
    Title: Genomic sequencing and editing revealed the GRM8 signaling pathway as potential therapeutic targets of squamous cell lung cancer.
  4. rs712723 in GRM8 was selected for genotyping. The allele C and genotype CC (allele C: OR 1.48, 95% CI 1.13-1.94; genotype CC: OR 1.71, 95% CI 1.09-2.68) of rs712723 polymorphism was found to have a significant association with risk of schizophrenia while allele T (P = 0.003) and genotype TT (P = 0.028) frequencies were found lower in control patients.
    Title: TCF4 and GRM8 gene polymorphisms and risk of schizophrenia in an Iranian population: a case-control study.
  5. This study showed that GRM8 was nominally associated (p < 0.05) with both delta measures (energy and intertrial phase coherence).
    Title: What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude?
  6. Study represents a genetic association test towards single variant and multi-markers interaction of GRM7 and GRM8 genes in both schizophrenia and major depressive disorders in Han Chinese population
    Title: Significant association of GRM7 and GRM8 genes with schizophrenia and major depressive disorder in the Han Chinese population.
  7. These results further implicate the role of glutamate receptor genes such as GRM8 in the development of alcohol dependence.
    Title: Further Analyses of Genetic Association Between GRM8 and Alcohol Dependence Symptoms Among Young Adults.
  8. Genome wide association study and meta-analysis results detected rs6951643, a GRM8 genetic variant as suggestive marker for sporadic Creutzfeldt-Jakob disease risk mapping outside the PRNP region.
    Title: A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk.
  9. propose three potential human candidate genes for voluntary physical exercise levels (MC3R, CYP24A1, and GRM8).
    Title: A candidate syntenic genetic locus is associated with voluntary exercise levels in mice and humans.
  10. The GRM8 gene might play an important role in the pathogenesis of schizophrenia.
    Title: Association analysis of the GRM8 gene with schizophrenia in the Uygur Chinese population.
Submit: New GeneRIF Correction See all GeneRIFs (21)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study of carotid atherosclerosis in HIV-infected men.
EBI GWAS Catalog
Chemerin, a novel adipokine in the regulation of angiogenesis.
EBI GWAS Catalog
Genome-wide association scan of trait depression.
EBI GWAS Catalog
Salt-inducible kinase 3, SIK3, is a new gene associated with hearing.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ41058, MGC126724

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables glutamate receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables group III metabotropic glutamate receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled glutamate receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in visual perception TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
metabotropic glutamate receptor 8
Names
glutamate receptor, metabotropic 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029532.2 RefSeqGene

    Range
    5000..819343
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000845.3 → NP_000836.2  metabotropic glutamate receptor 8 isoform a precursor

    See identical proteins and their annotated locations for NP_000836.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), as well as variants 4 and 5, encodes isoform a.
    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533
    Consensus CDS
    CCDS5794.1
    UniProtKB/Swiss-Prot
    A4D0Y3, B0FZ74, B0M0L0, O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165
    UniProtKB/TrEMBL
    A8K2D2
    Related
    ENSP00000344173.2, ENST00000339582.7
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  2. NM_001127323.1 → NP_001120795.1  metabotropic glutamate receptor 8 isoform b precursor

    See identical proteins and their annotated locations for NP_001120795.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate donor splice site at the penultimate exon compared to transcript variant 1, resulting in an isoform (b) of the same length, but with 16 different amino acids at the C-terminus compared to isoform a. This variant was designated as HmGluR8b by Malherbe et al, 1999 (PMID:10216218). Variants 2 and 6 both encode the same isoform (b).
    Source sequence(s)
    AJ236921, AK315203, BG202742, BG211606
    Consensus CDS
    CCDS47696.1
    UniProtKB/TrEMBL
    A8K2D2
    Related
    ENSP00000351142.3, ENST00000358373.8
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  3. NM_001371083.1 → NP_001358012.1  metabotropic glutamate receptor 8 isoform a precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 1 and 5, encodes isoform a.
    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533, KF458593
    Consensus CDS
    CCDS5794.1
    UniProtKB/Swiss-Prot
    A4D0Y3, B0FZ74, B0M0L0, O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165
    UniProtKB/TrEMBL
    A8K2D2
    Related
    ENSP00000516625.1, ENST00000706917.1
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  4. NM_001371084.1 → NP_001358013.1  metabotropic glutamate receptor 8 isoform a precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 1 and 4, encodes isoform a.
    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533
    Consensus CDS
    CCDS5794.1
    UniProtKB/Swiss-Prot
    A4D0Y3, B0FZ74, B0M0L0, O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165
    UniProtKB/TrEMBL
    A8K2D2
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  5. NM_001371085.1 → NP_001358014.1  metabotropic glutamate receptor 8 isoform b precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variant 2, encodes isoform b.
    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533
    Consensus CDS
    CCDS47696.1
    UniProtKB/TrEMBL
    A8K2D2
    Related
    ENSP00000516624.1, ENST00000706916.1
    Conserved Domains (3) summary
    cd15454
    Location:582 → 892
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:512 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06376
    Location:40 → 504
    PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor

  6. NM_001371086.1 → NP_001358015.1  metabotropic glutamate receptor 8 isoform c precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) encodes the longest isoform (c).
    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533
    UniProtKB/TrEMBL
    A0A9L9PYG5, A8K2D2
    Related
    ENSP00000516623.1, ENST00000706915.1

  7. NM_001371087.1 → NP_001358016.1  metabotropic glutamate receptor 8 isoform d

    Status: REVIEWED

    Source sequence(s)
    AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533
    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  8. NM_001371088.1 → NP_001358017.1  metabotropic glutamate receptor 8 isoform e precursor

    Status: REVIEWED

    Source sequence(s)
    AC000099, AC000363, AC000367, AC002424, AC002497, AC002533

RNA

  1. NR_028041.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains an additional exon in the central coding region that results in a frameshift, compared to transcript variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). This variant was designated as HmGluR8c by Malherbe et al, 1999 (PMID:10216218).
    Source sequence(s)
    AJ236922, AK315203, BC093725, BG202742, BG211606
    Related
    ENST00000341617.7

  2. NR_163849.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC000099, AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533

  3. NR_163850.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC000363, AC000367, AC000369, AC000370, AC002057, AC002083, AC002424, AC002533

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    126438598..127252941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047420269.1 → XP_047276225.1  metabotropic glutamate receptor 8 isoform X1

  2. XM_047420271.1 → XP_047276227.1  metabotropic glutamate receptor 8 isoform X3

  3. XM_017012077.2 → XP_016867566.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  4. XM_047420272.1 → XP_047276228.1  metabotropic glutamate receptor 8 isoform X3

  5. XM_017012078.2 → XP_016867567.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  6. XM_047420270.1 → XP_047276226.1  metabotropic glutamate receptor 8 isoform X2

  7. XM_017012075.2 → XP_016867564.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  8. XM_017012076.2 → XP_016867565.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  9. XM_047420276.1 → XP_047276232.1  metabotropic glutamate receptor 8 isoform X3

  10. XM_017012079.2 → XP_016867568.1  metabotropic glutamate receptor 8 isoform X3

    Conserved Domains (3) summary
    cd15454
    Location:377 → 687
    7tmC_mGluR8; metabotropic glutamate receptor 8 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:307 → 357
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cl10011
    Location:1 → 299
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

  11. XM_047420275.1 → XP_047276231.1  metabotropic glutamate receptor 8 isoform X4

  12. XM_047420274.1 → XP_047276230.1  metabotropic glutamate receptor 8 isoform X4

  13. XM_047420273.1 → XP_047276229.1  metabotropic glutamate receptor 8 isoform X4

  14. XM_047420277.1 → XP_047276233.1  metabotropic glutamate receptor 8 isoform X5

RNA

  1. XR_007060010.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    127750296..128564614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054358000.1 → XP_054213975.1  metabotropic glutamate receptor 8 isoform X1

  2. XM_054358007.1 → XP_054213982.1  metabotropic glutamate receptor 8 isoform X3

  3. XM_054358002.1 → XP_054213977.1  metabotropic glutamate receptor 8 isoform X3

  4. XM_054358008.1 → XP_054213983.1  metabotropic glutamate receptor 8 isoform X3

  5. XM_054358005.1 → XP_054213980.1  metabotropic glutamate receptor 8 isoform X3

  6. XM_054358001.1 → XP_054213976.1  metabotropic glutamate receptor 8 isoform X2

  7. XM_054358003.1 → XP_054213978.1  metabotropic glutamate receptor 8 isoform X3

  8. XM_054358004.1 → XP_054213979.1  metabotropic glutamate receptor 8 isoform X3

  9. XM_054358012.1 → XP_054213987.1  metabotropic glutamate receptor 8 isoform X3

  10. XM_054358006.1 → XP_054213981.1  metabotropic glutamate receptor 8 isoform X3

  11. XM_054358011.1 → XP_054213986.1  metabotropic glutamate receptor 8 isoform X4

  12. XM_054358010.1 → XP_054213985.1  metabotropic glutamate receptor 8 isoform X4

  13. XM_054358009.1 → XP_054213984.1  metabotropic glutamate receptor 8 isoform X4

  14. XM_054358013.1 → XP_054213988.1  metabotropic glutamate receptor 8 isoform X5

RNA

  1. XR_008487567.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O00222.2 GenPept UniProtKB/Swiss-Prot:O00222

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