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Dera deoxyribose-phosphate aldolase [ Mus musculus (house mouse) ]

Gene ID: 232449, updated on 2-Nov-2024

Summary

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Official Symbol
Deraprovided by MGI
Official Full Name
deoxyribose-phosphate aldolaseprovided by MGI
Primary source
MGI:MGI:1913762
See related
Ensembl:ENSMUSG00000030225 AllianceGenome:MGI:1913762
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DEOC; 2010002D22Rik; 2500002K03Rik
Summary
Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process; deoxyribonucleoside catabolic process; and deoxyribonucleotide catabolic process. Predicted to be located in nucleoplasm. Orthologous to human DERA (deoxyribose-phosphate aldolase). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in placenta adult (RPKM 22.5), large intestine adult (RPKM 18.1) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Dera in Genome Data Viewer
Location:
6 G1; 6 67.32 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (137731093..137814894)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (137754577..137837872)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_17631 Neighboring gene predicted gene, 38915 Neighboring gene STARR-positive B cell enhancer ABC_E4877 Neighboring gene STARR-positive B cell enhancer ABC_E4878 Neighboring gene serine/threonine kinase receptor associated protein Neighboring gene STARR-seq mESC enhancer starr_17633 Neighboring gene predicted gene, 38552 Neighboring gene STARR-seq mESC enhancer starr_17634 Neighboring gene solute carrier family 15, member 5 Neighboring gene STARR-seq mESC enhancer starr_17635

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Bulusu V, et al. Dev Cell, 2017 Feb 27. PMID 28245920, Free PMC Article
  2. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables deoxyribose-phosphate aldolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deoxyribose-phosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
  
enables deoxyribose-phosphate aldolase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in carbohydrate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in deoxyribonucleoside catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in deoxyribonucleoside catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in deoxyribonucleotide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in deoxyribonucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in deoxyribose phosphate catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
deoxyribose-phosphate aldolase
Names
2-deoxy-D-ribose 5-phosphate aldolase
2-deoxyribose-5-phosphate aldolase homolog
deoxyriboaldolase
deoxyribose-phosphate aldolase (putative)
phosphodeoxyriboaldolase
putative deoxyribose-phosphate aldolase
NP_766321.1
XP_036021982.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172733.1 → NP_766321.1  deoxyribose-phosphate aldolase

    See identical proteins and their annotated locations for NP_766321.1

    Status: PROVISIONAL

    Source sequence(s)
    AK083298
    Consensus CDS
    CCDS20666.1
    UniProtKB/Swiss-Prot
    Q3UD33, Q91YP3, Q9CZI8
    UniProtKB/TrEMBL
    Q3THN2
    Related
    ENSMUSP00000084959.7, ENSMUST00000087675.9
    Conserved Domains (1) summary
    cd00959
    Location:50 → 277
    DeoC; 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    137731093..137814894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036166089.1 → XP_036021982.1  deoxyribose-phosphate aldolase isoform X1

    UniProtKB/TrEMBL
    Q3THN2
    Conserved Domains (1) summary
    cl21457
    Location:50 → 234
    TIM; TIM-like beta/alpha barrel domains
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q91YP3.1 GenPept UniProtKB/Swiss-Prot:Q91YP3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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