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Chd3 chromodomain helicase DNA binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 216848, updated on 2-Nov-2024

Summary

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Official Symbol
Chd3provided by MGI
Official Full Name
chromodomain helicase DNA binding protein 3provided by MGI
Primary source
MGI:MGI:1344395
See related
Ensembl:ENSMUSG00000018474 AllianceGenome:MGI:1344395
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Chd7; Prp7; Prp9-1; 2600010P09Rik
Summary
Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and histone binding activity. Acts upstream of or within chromatin organization. Part of NuRD complex. Is expressed in several structures, including cerebral cortex; early conceptus; genitourinary system; pancreas epithelium; and spleen. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in frontal lobe adult (RPKM 53.4), limb E14.5 (RPKM 46.3) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Chd3 in Genome Data Viewer
Location:
11 B3; 11 42.53 cM
Exon count:
42
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (69234099..69260325, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (69343273..69369499, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel, shaker-related subfamily, beta member 3 Neighboring gene ring finger protein 227 Neighboring gene predicted gene, 22442 Neighboring gene STARR-positive B cell enhancer ABC_E5240 Neighboring gene predicted gene, 32483 Neighboring gene STARR-positive B cell enhancer ABC_E7004 Neighboring gene cytochrome b5 domain containing 1 Neighboring gene transmembrane protein 88 Neighboring gene N(alpha)-acetyltransferase 38, NatC auxiliary subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Restricted expression of chromatin remodeling associated factor Chd3 during tooth root development. Date Y, et al. J Periodontal Res, 2012 Apr. PMID 21972924
  2. Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development. de Castro RO, et al. Epigenetics Chromatin, 2022 May 14. PMID 35568926, Free PMC Article
  3. The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development. Xie J, et al. PLoS One, 2020. PMID 32658897, Free PMC Article
  4. Mammalian chromodomain proteins: their role in genome organisation and expression. Jones DO, et al. Bioessays, 2000 Feb. PMID 10655032
  5. Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. Sillibourne JE, et al. Mol Biol Cell, 2007 Sep. PMID 17626165, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.
    Title: The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.
  2. results suggest that ZFH/Chd3 might play an important role in tooth root development and subsequent cementogenesis.
    Title: Restricted expression of chromatin remodeling associated factor Chd3 during tooth root development.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (4)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC40857

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity ISO
Inferred from Sequence Orthology
more info
  
enables ATP-dependent chromatin remodeler activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP-dependent chromatin remodeler activity ISO
Inferred from Sequence Orthology
more info
  
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within chromatin organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in spindle organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of NuRD complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NuRD complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of NuRD complex ISO
Inferred from Sequence Orthology
more info
  
located_in PML body ISO
Inferred from Sequence Orthology
more info
  
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
  
located_in centrosome ISO
Inferred from Sequence Orthology
more info
  
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
chromodomain-helicase-DNA-binding protein 3
Names
Mi-2 alpha
NP_666131.3
XP_006532943.1
XP_006532944.1
XP_006532945.1
XP_006532946.1
XP_006532947.1
XP_006532948.1
XP_006532949.1
XP_006532950.1
XP_006532951.1
XP_006532952.1
XP_006532953.1
XP_017169944.1
XP_017169945.1
XP_030101674.1
XP_036012459.1
XP_036012460.1
XP_036012461.1
XP_036012462.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146019.4 → NP_666131.3  chromodomain-helicase-DNA-binding protein 3

    Status: VALIDATED

    Source sequence(s)
    AK045449, BC030435, BC060721, BM950040, BU702731, CJ119759
    Consensus CDS
    CCDS48825.2
    UniProtKB/TrEMBL
    B1AR17, F7C528
    Related
    ENSMUSP00000104301.2, ENSMUST00000108661.8
    Conserved Domains (11) summary
    smart00298
    Location:685 → 737
    CHROMO; Chromatin organization modifier domain
    cd00046
    Location:808 → 966
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    pfam00176
    Location:791 → 1087
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:1111 → 1226
    Helicase_C; Helicase conserved C-terminal domain
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1408
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 252
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1789 → 1960
    CHDCT2; CHDCT2 (NUC038) domain
    pfam16885
    Location:1627 → 1749
    CAC1F_C; Voltage-gated calcium channel subunit alpha, C-term

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    69234099..69260325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532881.2 → XP_006532944.1  chromodomain-helicase-DNA-binding protein 3 isoform X3

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:770 → 1324
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1588 → 1758
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:433 → 475
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:509 → 551
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:679 → 733
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:556 → 634
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:787 → 1018
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1429 → 1568
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1363 → 1406
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:199 → 252
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1789 → 1916
    CHDCT2; CHDCT2 (NUC038) domain

  2. XM_030245814.1 → XP_030101674.1  chromodomain-helicase-DNA-binding protein 3 isoform X7

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:761 → 1315
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1579 → 1749
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:424 → 466
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:500 → 542
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:670 → 724
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:547 → 625
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:778 → 1009
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1420 → 1559
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1354 → 1397
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1780 → 1907
    CHDCT2; CHDCT2 (NUC038) domain

  3. XM_006532882.2 → XP_006532945.1  chromodomain-helicase-DNA-binding protein 3 isoform X4

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:767 → 1321
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1585 → 1755
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:430 → 472
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:506 → 548
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:676 → 730
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:553 → 631
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:784 → 1015
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1426 → 1565
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1360 → 1403
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1786 → 1913
    CHDCT2; CHDCT2 (NUC038) domain

  4. XM_036156569.1 → XP_036012462.1  chromodomain-helicase-DNA-binding protein 3 isoform X14

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:765 → 1319
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1555 → 1740
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:428 → 470
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:504 → 546
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:674 → 728
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:551 → 629
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:782 → 1013
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1424 → 1563
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1360 → 1403
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1783 → 1909
    CHDCT2; CHDCT2 (NUC038) domain

  5. XM_006532883.2 → XP_006532946.1  chromodomain-helicase-DNA-binding protein 3 isoform X5

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:765 → 1319
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1583 → 1753
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:428 → 470
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:504 → 546
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:674 → 728
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:551 → 629
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:782 → 1013
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1424 → 1563
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1358 → 1401
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1784 → 1911
    CHDCT2; CHDCT2 (NUC038) domain

  6. XM_006532888.2 → XP_006532951.1  chromodomain-helicase-DNA-binding protein 3 isoform X16

    UniProtKB/TrEMBL
    E9Q614, F7C528
    Related
    ENSMUSP00000090649.7, ENSMUST00000092971.13
    Conserved Domains (11) summary
    TIGR02927
    Location:1572 → 1724
    SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1755 → 1926
    CHDCT2; CHDCT2 (NUC038) domain

  7. XM_017314456.2 → XP_017169945.1  chromodomain-helicase-DNA-binding protein 3 isoform X15

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    TIGR02927
    Location:1572 → 1725
    SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1756 → 1927
    CHDCT2; CHDCT2 (NUC038) domain

  8. XM_006532884.2 → XP_006532947.1  chromodomain-helicase-DNA-binding protein 3 isoform X10

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    TIGR02927
    Location:1572 → 1725
    SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1756 → 1883
    CHDCT2; CHDCT2 (NUC038) domain

  9. XM_006532880.2 → XP_006532943.1  chromodomain-helicase-DNA-binding protein 3 isoform X2

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1561 → 1746
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1789 → 1916
    CHDCT2; CHDCT2 (NUC038) domain

  10. XM_006532886.2 → XP_006532949.1  chromodomain-helicase-DNA-binding protein 3 isoform X12

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1589 → 1759
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1790 → 1961
    CHDCT2; CHDCT2 (NUC038) domain

  11. XM_017314455.2 → XP_017169944.1  chromodomain-helicase-DNA-binding protein 3 isoform X1

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1589 → 1759
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1790 → 1917
    CHDCT2; CHDCT2 (NUC038) domain

  12. XM_006532889.1 → XP_006532952.1  chromodomain-helicase-DNA-binding protein 3 isoform X17

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:551 → 1105
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1369 → 1539
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:214 → 256
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:290 → 332
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:460 → 514
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:337 → 415
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:568 → 799
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1210 → 1349
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1144 → 1187
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:1 → 33
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1570 → 1697
    CHDCT2; CHDCT2 (NUC038) domain

  13. XM_006532887.4 → XP_006532950.1  chromodomain-helicase-DNA-binding protein 3 isoform X13

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:716 → 1270
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1549 → 1704
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:379 → 421
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:455 → 497
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:625 → 679
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:502 → 580
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:733 → 964
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1375 → 1514
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1309 → 1352
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:145 → 198
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1735 → 1862
    CHDCT2; CHDCT2 (NUC038) domain

  14. XM_006532890.3 → XP_006532953.1  chromodomain-helicase-DNA-binding protein 3 isoform X18

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:770 → 1324
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1588 → 1758
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:433 → 475
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:509 → 551
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:679 → 733
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:556 → 634
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:787 → 1018
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1429 → 1568
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1363 → 1406
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:199 → 252
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1789 → 1960
    CHDCT2; CHDCT2 (NUC038) domain

  15. XM_036156568.1 → XP_036012461.1  chromodomain-helicase-DNA-binding protein 3 isoform X9

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:760 → 1314
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1550 → 1735
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:423 → 465
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:499 → 541
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:669 → 723
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:546 → 624
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:777 → 1008
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1419 → 1558
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1355 → 1398
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:199 → 252
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1778 → 1904
    CHDCT2; CHDCT2 (NUC038) domain

  16. XM_036156567.1 → XP_036012460.1  chromodomain-helicase-DNA-binding protein 3 isoform X8

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:761 → 1315
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1551 → 1736
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:424 → 466
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:500 → 542
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:670 → 724
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:547 → 625
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:778 → 1009
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1420 → 1559
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1356 → 1399
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1779 → 1905
    CHDCT2; CHDCT2 (NUC038) domain

  17. XM_036156566.1 → XP_036012459.1  chromodomain-helicase-DNA-binding protein 3 isoform X6

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    PLN03142
    Location:765 → 1319
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    PHA03169
    Location:1555 → 1740
    PHA03169; hypothetical protein; Provisional
    cd15531
    Location:428 → 470
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:504 → 546
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:674 → 728
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:551 → 629
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:782 → 1013
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1424 → 1563
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1360 → 1403
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1783 → 1909
    CHDCT2; CHDCT2 (NUC038) domain

  18. XM_006532885.2 → XP_006532948.1  chromodomain-helicase-DNA-binding protein 3 isoform X11

    UniProtKB/TrEMBL
    F7C528
    Conserved Domains (11) summary
    TIGR02927
    Location:1572 → 1724
    SucB_Actino; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase
    PLN03142
    Location:771 → 1325
    PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
    cd15531
    Location:434 → 476
    PHD1_CHD_II; PHD finger 1 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd15532
    Location:510 → 552
    PHD2_CHD_II; PHD finger 2 found in class II Chromodomain-Helicase-DNA binding (CHD) proteins
    cd18662
    Location:680 → 734
    CD2_tandem_CHD3-4_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18667
    Location:557 → 635
    CD1_tandem_CHD3-4_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 3 and 4, and similar proteins
    cd18055
    Location:788 → 1019
    DEXHc_CHD3; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 3
    pfam06461
    Location:1430 → 1569
    DUF1086; Domain of Unknown Function (DUF1086)
    pfam06465
    Location:1364 → 1407
    DUF1087; Domain of Unknown Function (DUF1087)
    pfam08073
    Location:200 → 253
    CHDNT; CHDNT (NUC034) domain
    pfam08074
    Location:1755 → 1882
    CHDCT2; CHDCT2 (NUC038) domain
Nucleotide Protein Strain
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