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Zeb1 zinc finger E-box binding homeobox 1 [ Mus musculus (house mouse) ]

Gene ID: 21417, updated on 2-Nov-2024

Summary

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Official Symbol
Zeb1provided by MGI
Official Full Name
zinc finger E-box binding homeobox 1provided by MGI
Primary source
MGI:MGI:1344313
See related
Ensembl:ENSMUSG00000024238 AllianceGenome:MGI:1344313
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tw; BZP; ZEB; MEB1; Nil2; Tcf8; AREB6; TCF-8; Tcf18; Zfhep; Zfx1a; Zfhx1a; Zfx1ha; [delta]EF1; 3110032K11Rik
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of neuron differentiation. Acts upstream of or within several processes, including embryonic organ morphogenesis; negative regulation of keratinocyte proliferation; and regulation of T cell differentiation in thymus. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study tropical spastic paraparesis. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3. Orthologous to human ZEB1 (zinc finger E-box binding homeobox 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 9.2), limb E14.5 (RPKM 8.6) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Zeb1 in Genome Data Viewer
Location:
18 4.42 cM; 18 A1
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (5591330..5775468)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (5591327..5775468)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43695 Neighboring gene predicted gene, 34630 Neighboring gene STARR-seq mESC enhancer starr_43697 Neighboring gene zinc finger E-box binding homeobox 1, opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:5591157-5591340 Neighboring gene STARR-positive B cell enhancer mm9_chr18:5591593-5591893 Neighboring gene predicted gene, 52340 Neighboring gene predicted gene 2238 Neighboring gene STARR-seq mESC enhancer starr_43699 Neighboring gene predicted gene, 34740 Neighboring gene predicted gene, 34804

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Pro-angiogenic role of ZEB1 in skin wound healing by upregulating VEGFA via microRNA-206 suppression. Lan H, et al. Exp Dermatol, 2022 Sep. PMID 35570385
  2. Decrease of ZEB1 expression inhibits the B16F10 cancer stem-like properties. Zhao F, et al. Biosci Trends, 2015 Oct. PMID 26559025
  3. Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth. Bak ST, et al. Basic Res Cardiol, 2023 Mar 2. PMID 36862248, Free PMC Article
  4. Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network. Gubelmann C, et al. Elife, 2014 Aug 27. PMID 25163748, Free PMC Article
  5. Upregulation of Microglial ZEB1 Ameliorates Brain Damage after Acute Ischemic Stroke. Li D, et al. Cell Rep, 2018 Mar 27. PMID 29590624

See all (232) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
    Title: Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
  2. Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis.
    Title: Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis.
  3. The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells.
    Title: The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells.
  4. ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
    Title: ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
  5. Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
    Title: Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
  6. The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
    Title: The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.
  7. PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
    Title: PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
  8. The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells.
    Title: The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells.
  9. LncRNA LINC00667 gets involved in clear cell renal cell carcinoma development and chemoresistance by regulating the miR-143-3p/ZEB1 axis.
    Title: LncRNA LINC00667 gets involved in clear cell renal cell carcinoma development and chemoresistance by regulating the miR-143-3p/ZEB1 axis.
  10. ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
    Title: ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
Submit: New GeneRIF Correction See all GeneRIFs (116)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables E-box binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
  
enables double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within animal organ development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cartilage development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to amino acid stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to transforming growth factor beta stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within central nervous system development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within cochlea morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryonic camera-type eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within embryonic morphogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within embryonic skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in forebrain development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of keratinocyte proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of endothelial cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of endothelial cell differentiation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within negative regulation of epithelial cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of keratinocyte proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within pattern specification process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of neuron differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of T cell differentiation in thymus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of mesenchymal cell proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of smooth muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of transforming growth factor beta receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in response to activity IEA
Inferred from Electronic Annotation
more info
  
involved_in response to nutrient levels IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within semicircular canal morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger E-box-binding homeobox 1
Names
transcription factor 8
twirler
zinc finger homeobox protein 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360981.1 → NP_001347910.1  zinc finger E-box-binding homeobox 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC127028, AC138619
    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (4) summary
    smart00389
    Location:554 → 590
    HOX; Homeodomain
    sd00017
    Location:867 → 887
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:203 → 225
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:907 → 932
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001360982.1 → NP_001347911.1  zinc finger E-box-binding homeobox 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC127028, AC138619
    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  3. NM_011546.3 → NP_035676.1  zinc finger E-box-binding homeobox 1 isoform 1

    See identical proteins and their annotated locations for NP_035676.1

    Status: VALIDATED

    Source sequence(s)
    AC127028, AK034821, BC139769, BE852657
    Consensus CDS
    CCDS29039.1
    UniProtKB/Swiss-Prot
    A4QPD2, Q62519, Q64318
    UniProtKB/TrEMBL
    A4QPD1
    Related
    ENSMUSP00000025081.6, ENSMUST00000025081.13
    Conserved Domains (4) summary
    smart00389
    Location:571 → 607
    HOX; Homeodomain
    sd00017
    Location:884 → 904
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:220 → 242
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:924 → 949
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    5591330..5775468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250410.2 → XP_030106270.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  2. XM_030250409.2 → XP_030106269.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  3. XM_030250411.2 → XP_030106271.1  zinc finger E-box-binding homeobox 1 isoform X4

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (4) summary
    smart00389
    Location:504 → 540
    HOX; Homeodomain
    sd00017
    Location:817 → 837
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:153 → 175
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:857 → 882
    zf-H2C2_2; Zinc-finger double domain

  4. XM_036161065.1 → XP_036016958.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  5. XM_030250401.1 → XP_030106261.1  zinc finger E-box-binding homeobox 1 isoform X1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  6. XM_030250405.2 → XP_030106265.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  7. XM_030250400.2 → XP_030106260.1  zinc finger E-box-binding homeobox 1 isoform X1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  8. XM_030250406.2 → XP_030106266.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  9. XM_036161061.1 → XP_036016954.1  zinc finger E-box-binding homeobox 1 isoform X1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  10. XM_006525769.4 → XP_006525832.1  zinc finger E-box-binding homeobox 1 isoform X1

    See identical proteins and their annotated locations for XP_006525832.1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  11. XM_036161062.1 → XP_036016955.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  12. XM_036161059.1 → XP_036016952.1  zinc finger E-box-binding homeobox 1 isoform X1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  13. XM_030250407.2 → XP_030106267.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  14. XM_030250404.2 → XP_030106264.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  15. XM_036161068.1 → XP_036016961.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  16. XM_036161067.1 → XP_036016960.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  17. XM_030250402.2 → XP_030106262.1  zinc finger E-box-binding homeobox 1 isoform X2

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (4) summary
    smart00389
    Location:557 → 593
    HOX; Homeodomain
    sd00017
    Location:870 → 890
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:206 → 228
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:910 → 935
    zf-H2C2_2; Zinc-finger double domain

  18. XM_030250399.2 → XP_030106259.1  zinc finger E-box-binding homeobox 1 isoform X1

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:877 → 897
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213 → 235
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:917 → 942
    zf-H2C2_2; Zinc-finger double domain

  19. XM_036161066.1 → XP_036016959.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  20. XM_036161069.1 → XP_036016962.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  21. XM_036161063.1 → XP_036016956.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  22. XM_036161064.1 → XP_036016957.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain

  23. XM_036161070.1 → XP_036016963.1  zinc finger E-box-binding homeobox 1 isoform X3

    UniProtKB/TrEMBL
    A4QPD1
    Conserved Domains (3) summary
    sd00017
    Location:828 → 848
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:164 → 186
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:868 → 893
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q64318.1 GenPept UniProtKB/Swiss-Prot:Q64318

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