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nhr-59 NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-59 [ Caenorhabditis elegans ]

Gene ID: 178707, updated on 2-Nov-2024

Summary

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Official Symbol
nhr-59
Official Full Name
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-59
Primary source
WormBase:WBGene00003649
Locus tag
CELE_T27B7.1
See related
AllianceGenome:WB:WBGene00003649
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nhr-59 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (2276013..2278265, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene ncRNA Neighboring gene DUF38 domain-containing protein Neighboring gene NR LBD domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Changes in Nuclear Receptor and Vitellogenin Gene Expression in Response to Steroids and Heavy Metal in Caenorhabditis elegans. Novillo A, et al. Integr Comp Biol, 2005 Jan. PMID 21676746
  2. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-59
NP_001303749.1
  • Confirmed by transcript evidence
NP_503624.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2276013..2278265 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071223.8 → NP_503624.2  Nuclear hormone receptor family member nhr-59 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503624.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9GTF2, Q9TXJ1
    Conserved Domains (2) summary
    smart00399
    Location:20 → 71
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    pfam00104
    Location:182 → 392
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor

  2. NM_001316820.3 → NP_001303749.1  NR LBD domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M9JJE1
    Conserved Domains (1) summary
    pfam00104
    Location:96 → 313
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TXJ1.2

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