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nhr-11 NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-11 [ Caenorhabditis elegans ]

Gene ID: 177724, updated on 2-Nov-2024

Summary

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Official Symbol
nhr-11
Official Full Name
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-11
Primary source
WormBase:WBGene00003610
Locus tag
CELE_ZC410.1
See related
AllianceGenome:WB:WBGene00003610
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in body wall; head ganglion; and head neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nhr-11 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
11
Sequence:
Chromosome: IV; NC_003282.8 (9070003..9073622)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mitochondrial-processing peptidase subunit beta Neighboring gene alpha-1,2-Mannosidase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
  2. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
  3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-11
NP_001041063.1
  • Confirmed by transcript evidence
NP_001041064.2
  • Confirmed by transcript evidence
NP_001255359.1
  • Confirmed by transcript evidence
NP_001255360.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9070003..9073622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268430.4 → NP_001255359.1  Nuclear hormone receptor family member nhr-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255359.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9G2T1
    Conserved Domains (2) summary
    smart00399
    Location:4 → 74
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    smart00430
    Location:244 → 423
    HOLI; Ligand binding domain of hormone receptors

  2. NM_001047598.3 → NP_001041063.1  Nuclear hormone receptor family member nhr-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041063.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q1NZ29, Q23294
    UniProtKB/TrEMBL
    Q5VKT4
    Conserved Domains (2) summary
    smart00399
    Location:4 → 77
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    smart00430
    Location:247 → 426
    HOLI; Ligand binding domain of hormone receptors

  3. NM_001047599.4 → NP_001041064.2  Nuclear hormone receptor family member nhr-11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041064.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23294
    Conserved Domains (1) summary
    smart00430
    Location:130 → 309
    HOLI; Ligand binding domain of hormone receptors

  4. NM_001268431.3 → NP_001255360.1  NR LBD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255360.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9G2T0
    Conserved Domains (1) summary
    smart00430
    Location:65 → 244
    HOLI; Ligand binding domain of hormone receptors

RNA

  1. NR_003464.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q23294.3

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