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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001413769.1 → NP_001400698.1 guanine nucleotide exchange factor DBS isoform 2
Status: VALIDATED
- Source sequence(s)
-
JAXUCZ010000016
- Related
- ENSRNOP00000083374.2, ENSRNOT00000100402.2
-
NM_053951.2 → NP_446403.2 guanine nucleotide exchange factor DBS isoform 1
See identical proteins and their annotated locations for NP_446403.2
Status: VALIDATED
- Source sequence(s)
-
CH473970
- UniProtKB/TrEMBL
- A6IWK6, D4A7F3
- Conserved Domains (6) summary
-
- cd11857
Location:1082 → 1134
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:46 → 191
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:603 → 780
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:322 → 524
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:787 → 918
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- pfam00169
Location:801 → 915
- PH; PH domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086034.1 Reference GRCr8
- Range
-
83209277..83355683 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_039094165.2 → XP_038950093.1 guanine nucleotide exchange factor DBS isoform X8
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Related
- ENSRNOP00000077897.2, ENSRNOT00000101752.2
- Conserved Domains (5) summary
-
- cd11857
Location:1115 → 1167
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:76 → 221
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:633 → 810
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:352 → 554
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:817 → 948
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_039094166.2 → XP_038950094.1 guanine nucleotide exchange factor DBS isoform X12
- UniProtKB/Swiss-Prot
-
Q63406
- UniProtKB/TrEMBL
-
D4A7F3
- Related
- ENSRNOP00000068993.2, ENSRNOT00000079096.3
- Conserved Domains (5) summary
-
- cd11857
Location:1059 → 1111
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:76 → 221
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:633 → 810
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:352 → 554
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:817 → 948
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_063275044.1 → XP_063131114.1 guanine nucleotide exchange factor DBS isoform X16
-
XM_017599979.3 → XP_017455468.1 guanine nucleotide exchange factor DBS isoform X11
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
-
XM_006253421.5 → XP_006253483.1 guanine nucleotide exchange factor DBS isoform X6
- UniProtKB/TrEMBL
- A0A8I5ZZZ7, D4A7F3
- Conserved Domains (6) summary
-
- cd11857
Location:1128 → 1180
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- pfam00169
Location:900 → 1014
- PH; PH domain
-
XM_039094163.2 → XP_038950091.1 guanine nucleotide exchange factor DBS isoform X7
- UniProtKB/TrEMBL
-
D4A7F3
- Conserved Domains (5) summary
-
- cd11857
Location:1128 → 1180
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_039094162.2 → XP_038950090.1 guanine nucleotide exchange factor DBS isoform X4
- UniProtKB/TrEMBL
- A0A8I5Y6G8, A0A8I5ZWU6
- Conserved Domains (5) summary
-
- cd11857
Location:1153 → 1205
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_039094160.2 → XP_038950088.1 guanine nucleotide exchange factor DBS isoform X3
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Conserved Domains (5) summary
-
- cd11857
Location:1181 → 1233
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_006253416.5 → XP_006253478.1 guanine nucleotide exchange factor DBS isoform X1
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Related
- ENSRNOP00000085354.2, ENSRNOT00000111168.2
- Conserved Domains (6) summary
-
- cd11857
Location:1184 → 1236
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- pfam00169
Location:900 → 1014
- PH; PH domain
-
XM_039094159.2 → XP_038950087.1 guanine nucleotide exchange factor DBS isoform X2
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Conserved Domains (5) summary
-
- cd11857
Location:1184 → 1236
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:145 → 290
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:702 → 879
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:421 → 623
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:886 → 1017
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_006253423.5 → XP_006253485.1 guanine nucleotide exchange factor DBS isoform X9
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Conserved Domains (6) summary
-
- cd11857
Location:1089 → 1141
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:50 → 195
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:607 → 784
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:326 → 528
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:791 → 922
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- pfam00169
Location:805 → 919
- PH; PH domain
-
XM_039094167.2 → XP_038950095.1 guanine nucleotide exchange factor DBS isoform X13
- UniProtKB/TrEMBL
- A0A8L2QMZ3, D4A7F3
- Related
- ENSRNOP00000047024.6, ENSRNOT00000043170.8
- Conserved Domains (5) summary
-
- cd11857
Location:1033 → 1085
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:50 → 195
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:607 → 784
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:326 → 528
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:791 → 922
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
-
XM_063275040.1 → XP_063131110.1 guanine nucleotide exchange factor DBS isoform X5
-
XM_006253424.5 → XP_006253486.1 guanine nucleotide exchange factor DBS isoform X10
- UniProtKB/TrEMBL
- A0A0G2KA20, A0A8I5Y6G8
- Related
- ENSRNOP00000075224.2, ENSRNOT00000087095.3
- Conserved Domains (6) summary
-
- cd11857
Location:1083 → 1135
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- smart00516
Location:44 → 189
- SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
- cd00160
Location:601 → 778
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:320 → 522
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:785 → 916
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- pfam00169
Location:799 → 913
- PH; PH domain
-
XM_063275042.1 → XP_063131112.1 guanine nucleotide exchange factor DBS isoform X15
-
XM_063275041.1 → XP_063131111.1 guanine nucleotide exchange factor DBS isoform X14
-
XM_039094169.2 → XP_038950097.1 guanine nucleotide exchange factor DBS isoform X17
- UniProtKB/TrEMBL
-
A0A8I5Y6G8
- Conserved Domains (5) summary
-
- cd11857
Location:926 → 978
- SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
- cd00160
Location:444 → 621
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd00176
Location:163 → 365
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- cd01227
Location:628 → 759
- PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
- cl15787
Location:5 → 35
- SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...