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Rcbtb2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 [ Mus musculus (house mouse) ]

Gene ID: 105670, updated on 2-Nov-2024

Summary

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Official Symbol
Rcbtb2provided by MGI
Official Full Name
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2provided by MGI
Primary source
MGI:MGI:1917200
See related
Ensembl:ENSMUSG00000022106 AllianceGenome:MGI:1917200
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Chc1l; RC/BTB2; 2610028E02Rik; 2810420M18Rik
Summary
Acts upstream of or within several processes, including digestive tract development; hematopoietic or lymphoid organ development; and liver development. Located in acrosomal vesicle. Used to study malignant histiocytic disease. Orthologous to human RCBTB2 (RCC1 and BTB domain containing protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in thymus adult (RPKM 22.6), CNS E11.5 (RPKM 17.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rcbtb2 in Genome Data Viewer
Location:
14 D3; 14 38.66 cM
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (73376185..73421495)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (73138745..73184055)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene cysteinyl leukotriene receptor 2 Neighboring gene glycine cleavage system protein H (aminomethyl carrier) pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:73516811-73517104 Neighboring gene predicted gene, 35388 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:73518865-73519018 Neighboring gene predicted gene, 52109 Neighboring gene STARR-seq mESC enhancer starr_37111 Neighboring gene RB transcriptional corepressor 1 Neighboring gene microRNA 687 Neighboring gene STARR-seq mESC enhancer starr_37112 Neighboring gene VISTA enhancer mm1341 Neighboring gene lysophosphatidic acid receptor 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. RC/BTB2 is essential for formation of primary cilia in mammalian cells. Zhang L, et al. Cytoskeleton (Hoboken), 2015 Apr. PMID 25762510, Free PMC Article
  2. Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms. Spillane DR, et al. PLoS One, 2015. PMID 26291700, Free PMC Article
  3. Mouse RC/BTB2, a member of the RCC1 superfamily, localizes to spermatid acrosomal vesicles. Wang J, et al. PLoS One, 2012. PMID 22768142, Free PMC Article
  4. Functional consequences of necdin nucleocytoplasmic localization. Lavi-Itzkovitz A, et al. PLoS One, 2012. PMID 22442722, Free PMC Article
  5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (2)  1 citation

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within digestive tract development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within liver development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within lymph node development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within spleen development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RCC1 and BTB domain-containing protein 2
Names
regulator of chromosome condensation and BTB domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170694.1 → NP_001164165.1  RCC1 and BTB domain-containing protein 2

    See identical proteins and their annotated locations for NP_001164165.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA119207, AK031248, AK160881, CX209814
    Consensus CDS
    CCDS27266.1
    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Related
    ENSMUSP00000131588.2, ENSMUST00000164822.8
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  2. NM_134083.4 → NP_598844.3  RCC1 and BTB domain-containing protein 2

    See identical proteins and their annotated locations for NP_598844.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA119207, AK031242, AK160881, CX209814
    Consensus CDS
    CCDS27266.1
    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Related
    ENSMUSP00000022702.7, ENSMUST00000022702.13
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

RNA

  1. NR_033185.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    CT571265

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    73376185..73421495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518384.2 → XP_006518447.1  RCC1 and BTB domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006518447.1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  2. XM_006518386.3 → XP_006518449.1  RCC1 and BTB domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006518449.1

    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (3) summary
    COG5184
    Location:83 → 311
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:350 → 466
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:463 → 527
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  3. XM_006518388.3 → XP_006518451.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  4. XM_011244891.4 → XP_011243193.1  RCC1 and BTB domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011243193.1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  5. XM_036158375.1 → XP_036014268.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  6. XM_036158377.1 → XP_036014270.1  RCC1 and BTB domain-containing protein 2 isoform X5

    Conserved Domains (2) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cl38908
    Location:214 → 303
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  7. XM_030247592.2 → XP_030103452.1  RCC1 and BTB domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (2) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cl38908
    Location:374 → 463
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  8. XM_011244892.4 → XP_011243194.1  RCC1 and BTB domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (2) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cl38908
    Location:374 → 463
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  9. XM_006518382.4 → XP_006518445.1  RCC1 and BTB domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006518445.1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Related
    ENSMUSP00000127397.2, ENSMUST00000171767.8
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  10. XM_030247593.1 → XP_030103453.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  11. XM_036158373.1 → XP_036014266.1  RCC1 and BTB domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  12. XM_036158376.1 → XP_036014269.1  RCC1 and BTB domain-containing protein 2 isoform X5

    Conserved Domains (2) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cl38908
    Location:214 → 303
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  13. XM_036158374.1 → XP_036014267.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  14. XM_030247591.2 → XP_030103451.1  RCC1 and BTB domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    E9Q3B1
    Related
    ENSMUSP00000128579.2, ENSMUST00000169513.8
    Conserved Domains (3) summary
    COG5184
    Location:83 → 311
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:350 → 466
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:463 → 527
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  15. XM_006518385.4 → XP_006518448.1  RCC1 and BTB domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006518448.1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  16. XM_030247595.2 → XP_030103455.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  17. XM_006518383.4 → XP_006518446.1  RCC1 and BTB domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006518446.1

    UniProtKB/Swiss-Prot
    G1EE51, Q3TUA3, Q8BMG2, Q99LJ7
    UniProtKB/TrEMBL
    E9Q3B1
    Related
    ENSMUSP00000106577.4, ENSMUST00000110952.10
    Conserved Domains (3) summary
    COG5184
    Location:107 → 335
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:374 → 490
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:487 → 551
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)

  18. XM_030247594.2 → XP_030103454.1  RCC1 and BTB domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    COG5184
    Location:13 → 175
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    cd18354
    Location:214 → 330
    BTB_POZ_RCBTB2_CHC1L; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
    cd18529
    Location:327 → 391
    BACK_RCBTB2; BACK (BTB and C-terminal Kelch) domain found in RCC1 and BTB domain-containing protein 2 (RCBTB2)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99LJ7.1 GenPept UniProtKB/Swiss-Prot:Q99LJ7

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