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PPARA peroxisome proliferator activated receptor alpha [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100975411, updated on 3-Apr-2024

Summary

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Gene symbol
PPARA
Gene description
peroxisome proliferator activated receptor alpha
See related
Ensembl:ENSPPAG00000039570
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PPARA in Genome Data Viewer
Location:
chromosome: 23
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 23 NC_085927.1 (55981175..56072797)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 22 NC_073271.1 (58679171..58770754)

Chromosome 23 - NC_085927.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117978716 Neighboring gene microRNA let-7a-1 Neighboring gene microRNA let-7b Neighboring gene uncharacterized LOC134730098 Neighboring gene cysteine rich DPF motif domain containing 1 Neighboring gene polycystin family receptor for egg jelly

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hormone-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cholesterol storage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peroxisome proliferator-activated receptor alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_085927.1 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    55981175..56072797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034951723.3 → XP_034807614.1  peroxisome proliferator-activated receptor alpha

    UniProtKB/TrEMBL
    A0A2R9BY52
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  2. XM_034951724.3 → XP_034807615.1  peroxisome proliferator-activated receptor alpha

    UniProtKB/TrEMBL
    A0A2R9BY52
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  3. XM_008964792.5 → XP_008963040.1  peroxisome proliferator-activated receptor alpha

    See identical proteins and their annotated locations for XP_008963040.1

    UniProtKB/TrEMBL
    A0A2R9BY52
    Related
    ENSPPAP00000033410.1
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  4. XM_024927111.4 → XP_024782879.1  peroxisome proliferator-activated receptor alpha

    UniProtKB/TrEMBL
    A0A2R9BY52
    Conserved Domains (2) summary
    cd06932
    Location:201 → 466
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:101 → 184
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers

  5. XM_063603152.1 → XP_063459222.1  peroxisome proliferator-activated receptor alpha

    UniProtKB/TrEMBL
    A0A2R9BY52

  6. XM_063603151.1 → XP_063459221.1  peroxisome proliferator-activated receptor alpha

    UniProtKB/TrEMBL
    A0A2R9BY52
Nucleotide Protein
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