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Mta1 metastasis associated 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100754490, updated on 8-Mar-2024

Summary

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Gene symbol
Mta1
Gene description
metastasis associated 1
See related
Ensembl:ENSCGRG00015021464
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
20
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613702.1 (2682660..2708218)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 5 NC_048598.1 (180916170..180941867, complement)

NW_003613702.1Genomic Context describing neighboring genes Neighboring gene phosphofurin acidic cluster sorting protein 2 Neighboring gene testis expressed 22 Neighboring gene cysteine rich protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metastasis-associated protein MTA1
Names
Metastasis-associated protein MTA1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613702.1 Reference CriGri_1.0 Primary Assembly

    Range
    2682660..2708218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003498773.5 → XP_003498821.2  metastasis-associated protein MTA1 isoform X1

    UniProtKB/TrEMBL
    A0A8C2MUR3, A0A8C2QND7
    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048598.1 Alternate CriGri-PICRH-1.0

    Range
    180916170..180941867 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027416678.2 → XP_027272479.1  metastasis-associated protein MTA1 isoform X5

    UniProtKB/TrEMBL
    A0A8C2MZ32, A0A9J7FYX4
    Related
    ENSCGRP00015028493.2, ENSCGRT00015034887.2

  2. XM_027416677.2 → XP_027272478.1  metastasis-associated protein MTA1 isoform X4

    UniProtKB/TrEMBL
    A0A8C2MZ32, G3H3B1

  3. XM_027416676.2 → XP_027272477.1  metastasis-associated protein MTA1 isoform X3

    UniProtKB/TrEMBL
    A0A8C2MUR3, A0A9J7FZI7

  4. XM_027416675.2 → XP_027272476.1  metastasis-associated protein MTA1 isoform X2

    UniProtKB/TrEMBL
    A0A8C2MUR3, A0A9J7JQE7
    Related
    ENSCGRP00015046377.1, ENSCGRT00015053446.1

  5. XM_027416680.2 → XP_027272481.1  metastasis-associated protein MTA1 isoform X6

    UniProtKB/TrEMBL
    A0A9J7G318
Nucleotide Protein Strain
Heading Accession and Version

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