U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mta2 metastasis associated 1 family member 2 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100752944, updated on 8-Mar-2024

Summary

Gene symbol
Mta2
Gene description
metastasis associated 1 family member 2
Locus tag
I79_016746
See related
Ensembl:ENSCGRG00015004302
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Mta2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
19
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614577.1 (254141..263440)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 3 NC_048596.1 (51145399..51154847, complement)

NW_003614577.1Genomic Context describing neighboring genes Neighboring gene retinal outer segment membrane protein 1 Neighboring gene EMAP like 3 Neighboring gene 60S ribosomal protein L35 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene eukaryotic translation elongation factor 1 gamma

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
metastasis-associated protein MTA2
Names
metastasis-associated gene family, member 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614577.1 Reference CriGri_1.0 Primary Assembly

    Range
    254141..263440
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003508738.5XP_003508786.1  metastasis-associated protein MTA2 isoform X1

    See identical proteins and their annotated locations for XP_003508786.1

    UniProtKB/TrEMBL
    A0A061I8L9, A0A8C2LHX3
    Conserved Domains (6) summary
    smart00717
    Location:266313
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:267312
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:363413
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:366421
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    cd04709
    Location:3168
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:147198
    ELM2; ELM2 domain
  2. XM_035460021.1XP_035315912.1  metastasis-associated protein MTA2 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LHX3, A0A9J7GT80
    Conserved Domains (5) summary
    cd11661
    Location:267312
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:363413
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3168
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:147198
    ELM2; ELM2 domain
    pfam17226
    Location:449524
    MTA_R1; MTA R1 domain
  3. XM_035460022.1XP_035315913.1  metastasis-associated protein MTA2 isoform X3

    UniProtKB/TrEMBL
    G3I069
    Conserved Domains (4) summary
    cd11661
    Location:94139
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:190240
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    pfam01448
    Location:125
    ELM2; ELM2 domain
    pfam17226
    Location:276351
    MTA_R1; MTA R1 domain

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048596.1 Alternate CriGri-PICRH-1.0

    Range
    51145399..51154847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027408334.2XP_027264135.1  metastasis-associated protein MTA2 isoform X1

    UniProtKB/TrEMBL
    A0A061I8L9, A0A8C2LHX3
    Related
    ENSCGRP00015005531.1, ENSCGRT00015006834.2
  2. XM_035441989.1XP_035297880.1  metastasis-associated protein MTA2 isoform X3

    UniProtKB/TrEMBL
    G3I069
    Conserved Domains (4) summary
    cd11661
    Location:94139
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:190240
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    pfam01448
    Location:125
    ELM2; ELM2 domain
    pfam17226
    Location:276351
    MTA_R1; MTA R1 domain
  3. XM_035441988.1XP_035297879.1  metastasis-associated protein MTA2 isoform X2

    UniProtKB/TrEMBL
    A0A8C2LHX3, A0A9J7GT80
    Conserved Domains (5) summary
    cd11661
    Location:267312
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:363413
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3168
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:147198
    ELM2; ELM2 domain
    pfam17226
    Location:449524
    MTA_R1; MTA R1 domain