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SMAD1 SMAD family member 1 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100341544, updated on 8-Mar-2024

Summary

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Gene symbol
SMAD1
Gene description
SMAD family member 1
See related
Ensembl:ENSOCUG00000017920
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See SMAD1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 15 NC_067388.1 (16091353..16177038, complement)

Chromosome 15 - NC_067388.1Genomic Context describing neighboring genes Neighboring gene adenosine 5'-monophosphoramidase HINT1-like Neighboring gene metabolism of cobalamin associated A Neighboring gene uncharacterized LOC127483269 Neighboring gene uncharacterized LOC127483377 Neighboring gene translation initiation factor IF-2-like Neighboring gene OTU deubiquitinase 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067388.1 Chromosome 15 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables I-SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heteromeric SMAD protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mothers against decapentaplegic homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067388.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    16091353..16177038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008267390.3 → XP_008265612.1  mothers against decapentaplegic homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_008265612.1

    UniProtKB/TrEMBL
    A0A5F9CKV6
    Conserved Domains (2) summary
    cd10490
    Location:9 → 132
    MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
    cd10497
    Location:265 → 465
    MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

  2. XM_051820039.1 → XP_051675999.1  mothers against decapentaplegic homolog 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F9DQ42

  3. XM_051820038.1 → XP_051675998.1  mothers against decapentaplegic homolog 1 isoform X2

    UniProtKB/TrEMBL
    G1TER1

  4. XM_051820033.1 → XP_051675993.1  mothers against decapentaplegic homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CKV6

  5. XM_008267391.3 → XP_008265613.1  mothers against decapentaplegic homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_008265613.1

    UniProtKB/TrEMBL
    A0A5F9CKV6
    Related
    ENSOCUP00000034294.1
    Conserved Domains (2) summary
    cd10490
    Location:9 → 132
    MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
    cd10497
    Location:265 → 465
    MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

  6. XM_051820036.1 → XP_051675996.1  mothers against decapentaplegic homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CKV6

  7. XM_051820037.1 → XP_051675997.1  mothers against decapentaplegic homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CKV6

  8. XM_051820034.1 → XP_051675994.1  mothers against decapentaplegic homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F9CKV6
Nucleotide Protein
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