VDR vitamin D receptor [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: VDR
Gene description: vitamin D receptor
Locus tag: CR201_G0011714
See related: Ensembl:ENSPPYG00000004448
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	10	NC_071995.2 (45543229..45647457, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	12	NC_071997.1 (45544101..45648329, complement)

Chromosome 10 - NC_071995.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D10S16 (e-PCR)
- UniSTS:155756

WI-17447 (e-PCR)
- UniSTS:55150

1a36h4F-2R (e-PCR)
- UniSTS:463474

1b-2k (e-PCR)
- UniSTS:463475

1c-12h (e-PCR)
- UniSTS:463477

1f-1kb (e-PCR)
- UniSTS:463480

1f-2kb (e-PCR)
- UniSTS:463482

1f-4h (e-PCR)
- UniSTS:463483

1gB (e-PCR)
- UniSTS:463485

1gC (e-PCR)
- UniSTS:463486

VDR1a-40h (e-PCR)
- UniSTS:463498

VDR1d+7h (e-PCR)
- UniSTS:463499

VDRU1 (e-PCR)
- UniSTS:463500

VDRU2 (e-PCR)
- UniSTS:463501

VDRU3 (e-PCR)
- UniSTS:463502

VDRU4 (e-PCR)
- UniSTS:463503

VDRU6 (e-PCR)
- UniSTS:463506

VDR_1a-10h (e-PCR)
- UniSTS:463507

VDR_1a-36h2-For (e-PCR)
- UniSTS:463510

VDR_1a-36h3 (e-PCR)
- UniSTS:463511

VDR_1a-5h (e-PCR)
- UniSTS:463512

VDR_1ad (e-PCR)
- UniSTS:463513

VDR_Cdx-2 (e-PCR)
- UniSTS:463514

VDR_E1c (e-PCR)
- UniSTS:463515

VDR_E2 (e-PCR)
- UniSTS:463516

VDR_E5 (e-PCR)
- UniSTS:463519

VDR_E6 (e-PCR)
- UniSTS:463520

VDR_E78 (e-PCR)
- UniSTS:463521

VDR (e-PCR)
- UniSTS:503993

GDB:384887 (e-PCR)
- UniSTS:157116

RH17584 (e-PCR)
- UniSTS:5822

SHGC-142050 (e-PCR)
- UniSTS:171215

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables vitamin D response element binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: vitamin D3 receptor

Names: vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D3 receptor pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001133993.1 → NP_001127465.1 vitamin D3 receptor

See identical proteins and their annotated locations for NP_001127465.1

Status: PROVISIONAL

Source sequence(s)

CR859646

UniProtKB/TrEMBL

Q5R8V3

Conserved Domains (2) summary

cd06955
Location:16 → 122

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

cl11397
Location:124 → 381

NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_071995.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

45543229..45647457 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024256328.3 → XP_024112096.2 vitamin D3 receptor isoform X1
XM_009247660.4 → XP_009245935.2 vitamin D3 receptor isoform X2

UniProtKB/TrEMBL

A0A2J8WCZ8, H2NH30

Related

ENSPPYP00000005076.3

Conserved Domains (2) summary

cd06933
Location:174 → 476

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cd06955
Location:66 → 172

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers
XM_024256325.3 → XP_024112093.1 vitamin D3 receptor isoform X5

UniProtKB/TrEMBL

A0A2J8WCX8, A0A8I5TEF2

Conserved Domains (2) summary

cd06933
Location:124 → 426

NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily

cd06955
Location:16 → 122

NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers
XM_063711652.1 → XP_063567722.1 vitamin D3 receptor isoform X4
XM_063711651.1 → XP_063567721.1 vitamin D3 receptor isoform X3