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    GP second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein [ Tai Forest ebolavirus ]

    Gene ID: 9487535, updated on 18-Aug-2023

    Summary

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    Gene symbol
    GP
    Gene description
    second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein
    Locus tag
    CIEBOVp4
    Gene type
    protein coding
    RNA name
    sGP
    RefSeq status
    PROVISIONAL
    Organism
    Tai Forest ebolavirus (isolate: Tai Forest virus/H.sapiens-tc/CIV/1994/Pauleoula-CI, nat-host: Homo sapiens)
    Lineage
    Viruses; ssRNA viruses; ssRNA negative-strand viruses; Mononegavirales; Filoviridae; Ebolavirus
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    Genomic context

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    Sequence:
    NC_014372.1 (5888..8293)

    NC_014372.1Genomic Context describing neighboring genes Neighboring gene nucleoprotein Neighboring gene polymerase complex protein Neighboring gene matrix protein Neighboring gene minor nucleoprotein Neighboring gene membrane-associated protein Neighboring gene RNA-dependent RNA polymerase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_014372.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. Towner JS, et al. PLoS Pathog, 2008 Nov. PMID 19023410, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Miscellaneous features

    • Loc: 6906-6912 additional A residues are inserted or deleted during transcription by the viral polymerase; transcriptional editing site
    • Loc: 7781-7858 immunosuppressive motif in structural glycoprotein
    • Loc: 7976-8041 transmembrane anchor present in structural glycoprotein

    regulatory

    • Loc: 5888-5899 regulatory_class = other
    • Loc: 8276-8287 regulatory_class = other
    • Loc: 8283-8293 regulatory_class = polyA_signal_sequence

    General protein information

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    Preferred Names
    second secreted glycoprotein;small secreted glycoprotein;spike glycoprotein
    YP_003815426.1
    • GP1,2; structural glycoprotein; cleaved by furin into subunits GP1 and GP2 to yield a heterodimer linked by a disulfide bond
    YP_003815427.1
    • soluble secreted glycoprotein; small non-structural secreted glycoprotein; sGP
    YP_003815428.1
    • ssGP; second non-structural secreted glycoprotein; secreted in a monomeric form; one A residue is deleted or two additional A residues are inserted at the editing site during transcription of the GP gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_014372.1 Reference assembly

      Range
      5888..8293
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_003815426.1 spike glycoprotein [Tai Forest ebolavirus]

      See identical proteins and their annotated locations for YP_003815426.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q66810
      UniProtKB/TrEMBL
      A0A2U8KL96, B8XCN9
      Conserved Domains (2) summary
      cd09850
      Location:557 → 629
      Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains
      pfam01611
      Location:15 → 348
      Filo_glycop; Filovirus glycoprotein

    2. YP_003815427.1 small secreted glycoprotein [Tai Forest ebolavirus]

      See identical proteins and their annotated locations for YP_003815427.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q66811
      UniProtKB/TrEMBL
      A0A2U8KL90, B8XCP0
      Conserved Domains (1) summary
      pfam01611
      Location:15 → 300
      Filo_glycop; Filovirus glycoprotein

    3. YP_003815428.1 second secreted glycoprotein [Tai Forest ebolavirus]

      See identical proteins and their annotated locations for YP_003815428.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2U8KL87, B8XCP1
      Conserved Domains (1) summary
      pfam01611
      Location:15 → 295
      Filo_glycop; Filovirus glycoprotein
    Nucleotide Protein
    Heading Accession and Version

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