Graph Theory and Brain Connectivity in Alzheimer's Disease

Neuroscientist. 2017 Dec;23(6):616-626. doi: 10.1177/1073858417702621. Epub 2017 Apr 13.

Abstract

This article presents a review of recent advances in neuroscience research in the specific area of brain connectivity as a potential biomarker of Alzheimer's disease with a focus on the application of graph theory. The review will begin with a brief overview of connectivity and graph theory. Then resent advances in connectivity as a biomarker for Alzheimer's disease will be presented and analyzed.

Keywords: Alzheimer’s disease; EEG; computational neuroscience; fMRI; graph theory.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / diagnostic imaging
  • Alzheimer Disease / physiopathology*
  • Brain / diagnostic imaging
  • Brain / physiopathology*
  • Connectome / methods*
  • Humans
  • Models, Theoretical
  • Neural Pathways / diagnostic imaging
  • Neural Pathways / physiopathology
  • Signal Processing, Computer-Assisted